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- Table of Contents
CHAT Antibodies
AND CHAT ELISA kits, CHAT Proteins
Many biological assays use antibodies to detect CHAT, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CHAT in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CHAT antibodies...
Designing a Western blot for CHAT? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CHAT Western Blot GuideCHAT Infographic by Boster Bio
All CHAT Products
Product
Figures
Specificity
Applications
Price
Mouse, Rat
ELISA, IHC, WB
$370
Cat # A01192-5
100 μg/vial
Cat # A01192-5
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01192-4
100 μg/vial
Cat # A01192-4
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # A01192-3
100 μg/vial
Cat # A01192-3
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A01192-6
100 μg/vial
Cat # A01192-6
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01192
100 μl
Cat # M01192
100 μl
Mouse, Rat
IHC, WB
$370
Cat # M01192-2
100 µl/vial
Cat # M01192-2
100 µl/vial
Human
$960
Cat # LS001103
20 µg, 100 µg
Cat # LS001103
20 µg, 100 µg
CHAT Overview
Facts about Choline O-acetyltransferase.
Choline O-acetyltransferase (CHAT)
Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline in cholinergic synapses. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CHAT |
| Uniprot: | P28329 |
| Entrez: | 1103 |
Family
| Belongs to: |
|---|
| carnitine/choline acetyltransferase family |
Alternative Names
acetyl CoA:choline O-acetyltransferase; CHAT; CHOACTase; Choline acetylase; Choline Acetyltransferase; choline O-acetyltransferase; CMS1A; CMS1A2; EC 2.3.1; EC 2.3.1.6
Molecular Weight
Mass (kDA):
82.536 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 10q11.23 |
| Sequence: | 10; NC_000010.11 (49609095..49665104) |
Diseases
- Alzheimer's Disease
- Nervousness
- Nerve Degeneration
- Dementia
- Malnutrition
- Memory Impairment
- Impaired Cognition
- Impairment (finding)
- Neurodegenerative Disorders
- Disease Of Adrenal Medulla
- Neurotoxicity Syndromes
- Varicosity
- Cri Du Chat
Pathways
- Innervation
- Localization
- Transport
- Aging
- Cell Death
- Pathogenesis
- Regeneration
- Cognition
- Secretion
- Neuroprotection
- Neurogenesis
- Brain Development
- Reflex
PTMs
- Phosphorylation
- Reduction
- Cleavage
- Biotinylation
- Acetylation
- Oxidation
- Carboxylation
- Prenylation
- Nitration
Research Areas
- Cellular Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CHAT
bosterbio.com/bosterbio-gene-info-cards/CHAT
References
PMID: 1337937 by Oda Y., et al. A complementary DNA for human choline acetyltransferase induces two forms of enzyme with different molecular weights in cultured cells.
PMID: 11172068 by Ohno K., et al. Choline acetyltransferase mutations cause myasthenic syndrome associated with episodic apnea in humans.
17 Publications of Boster CHAT Antibodies & ELISA Kits
- PubMed ID: 10.1186/s12872-016-0375-3, Autonomic remodeling may be responsible for decreased incidence of aortic dissec...
- PubMed ID: 10.1155/2021/9974625, Icariin Promotes Survival, Proliferation, and Differentiation of Neural Stem Cel...
- PubMed ID: 10.1155/2015/857202, Overexpression of NTRK1 Promotes Differentiation of Neural Stem Cells into Choli...
- PubMed ID: 10.1111/j.1527-3458.2007.00031.x, Protection of Mouse Brain from Aluminum‐induced Damage by Caffeic Acid
- PubMed ID: 10.1111/j.1440-1681.2009.05149.x, PROTECTIVE EFFECTS OF ICARIIN ON COGNITIVE DEFICITS INDUCED BY CHRONIC CEREBRAL ...
- PubMed ID: 10.1111/cns.12187, Activation of Muscarinic Receptors Protects against Retinal Neurons Damage and O...
- PubMed ID: 10.1016/S1673-5374(07)60016-4, Choline acetyltransferase expressed by radial neuroglia cells in the development...
- PubMed ID: 10.1007/s12031-018-1098-y, Pre-Injection of Small Interfering RNA (siRNA) Promotes c-Jun Gene Silencing and...
- PubMed ID: 10.1007/s11596-009-0404-x, Culture of motor neurons from newborn rat spinal cord
- PubMed ID: 18983683, Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineura...
- PubMed ID: 27769178, Autonomic remodeling may be responsible for decreased incidence of aortic dissec...
- PubMed ID: 26509167, Overexpression of NTRK1 Promotes Differentiation of Neural Stem Cells into Choli...
- PubMed ID: 18983651, Thalidomide influences growth and vasculogenic mimicry channel formation in mela...
- PubMed ID: 28102288, Yu H, Xia H, Tang Q, Xu H, Wei G, Chen Y, Dai X, Gong Q, Bi F. Sci Rep. 2017 Jan...
- PubMed ID: 29197398, Zhao D, Xu X, Pan L, Zhu W, Fu X, Guo L, Lu Q, Wang J. J Neuroinflammation. 2017...
- PubMed ID: 25657680, Liu B, Deng C, Zhang Y, Zhang J. Neural Regen Res. 2012 Jul 5;7(19):1463-8. Doi:...
- PubMed ID: 21674199, Wu R, Gu B, Zhao X, Tan Z, Chen L, Zhu J, Zhang M. Hum Cell. 2013 Mar;26(1):19-2...
*More publications can be found for each product on its corresponding product page