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- Table of Contents
CNP Antibodies
AND CNP ELISA kits, CNP Proteins
Many biological assays use antibodies to detect CNP, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CNP in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CNP antibodies...
Designing a Western blot for CNP? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CNP Western Blot GuideCNP Infographic by Boster Bio
All CNP Products
Product
Figures
Specificity
Applications
Price
Anti-CNPase/CNP Antibody Picoband®
2 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A01017-4
100 μg/vial
Cat # A01017-4
100 μg/vial
CNP Overview
Facts about 2',3'-cyclic-nucleotide 3'-phosphodiesterase.
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP)
May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | CNP |
| Uniprot: | P09543 |
| Entrez: | 1267 |
Family
| Belongs to: |
|---|
| 2H phosphoesterase superfamily |
Alternative Names
2', 3' cyclic nucleotide 3' phosphohydrolase; 2'-3'-cyclic nucleotide 3' phosphodiesterase; 2'-3'-cyclic-nucleotide 3'-phosphodiesterase; CNP1; CNPase; EC 3.1.4.37
Molecular Weight
Mass (kDA):
47.579 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17q21.2 |
| Sequence: | 17; NC_000017.11 (41966795..41977740) |
Subcellular Localizations
Membrane; Lipid-anchor. Melanosome. Firmly bound to membrane structures of brain white matter. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Diseases
- Nervousness
- Heart Failure
- Hypertensive Disease
- Cardiovascular Diseases
- Hypertrophy
- Neoplasms
- Multiple Sclerosis
- Sclerosis
- Pituitary Diseases
- Demyelinating Diseases
- Inflammation
- Demyelination
- Glioma
Pathways
- Secretion
- Myelination
- Localization
- Excretion
- Cell Proliferation
- Pathogenesis
- Natriuresis
- Transport
- Vasodilation
- Ossification
- Oligodendrocyte Differentiation
- Endochondral Ossification
- Diuresis
PTMs
- Phosphorylation
- Cleavage
- Prenylation
- Reduction
- Iodination
- Glycosylation
- Dephosphorylation
- Oxidation
- Nitration
Research Areas
- Cellular Markers
- Glia Markers
- Neuronal Cell Markers
- Neuroscience
- Oligodendrocyte Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CNP
bosterbio.com/bosterbio-gene-info-cards/CNP
References
PMID: 1385234 by Thompson R.J.; 2',3'-cyclic nucleotide-3'-phosphohydrolase and signal transduction in central nervous system myelin.
PMID: 2835044 by Kurihara T., et al. cDNA cloning and amino acid sequence of human brain 2',3'-cyclic- nucleotide 3'-phosphodiesterase.
3 Publications of Boster CNP Antibodies & ELISA Kits
- PubMed ID: 10.7150/ijbs.16823, Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxid...
- PubMed ID: 10.3109/10799893.2016.1155068, Neutral endopeptidase and natriuretic peptide receptors participate in the regul...
- PubMed ID: 27994507, Catalpol Protects Pre-Myelinating Oligodendrocytes against Ischemia-induced Oxid...
*More publications can be found for each product on its corresponding product page