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- Table of Contents
COL7A1 Antibodies
AND COL7A1 ELISA kits, COL7A1 Proteins
Many biological assays use antibodies to detect COL7A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with COL7A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop COL7A1 antibodies...
Designing a Western blot for COL7A1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the COL7A1 Western Blot GuideDesigning an IHC experiment for COL7A1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the COL7A1 IHC GuideCOL7A1 Infographic by Boster Bio
All COL7A1 Products
Product
Figures
Specificity
Applications
Price
Anti-Collagen VII/COL7A1 Antibody Picoband®
4 Citations
Human
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01170-1
100 μg/vial
Cat # A01170-1
100 μg/vial
COL7A1 Overview
Facts about Collagen alpha-1(VII) chain.
Collagen alpha-1(VII) chain (COL7A1)
Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen. .
Gene Information
| Human | |
|---|---|
| Gene Name: | COL7A1 |
| Uniprot: | Q02388 |
| Entrez: | 1294 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Collagen 7; collagen alpha-1(VII) chain; collagen VII, alpha-1 polypeptide; collagen, type VII, alpha 1; Collagen-7; EBD1; EBDCT; EBR1; epidermolysis bullosa, dystrophic, dominant and recessive; LC collagen; long chain collagen; Long-chain collagen
Molecular Weight
Mass (kDA):
295.22 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (48564073..48595329, complement) |
Subcellular Localizations
Secreted, extracellular space, extracellular matrix, basement membrane.
Diseases
- Epidermolysis Bullosa
- Epidermolysis Bullosa Dystrophica
- Hallopeau-siemens Disease
- Bulla
- Dermatologic Disorders
- Cockayne-touraine Disease
- Cicatrix
- Skin Diseases, Genetic
- Tissue Adhesions
- Pruritus
- Dystrophy
- Mucinous Adenocarcinoma
Interacting Proteins
- MIA3
Pathways
- Pathogenesis
- Secretion
- Translation
- Localization
- Wound Healing
- Cell Adhesion
- Cell Growth
- Keratinization
- Response To Wounding
- Immune Response
- Complement Activation
- Inflammatory Response
- Sensitization
PTMs
Research Areas
- Cell Biology
- Cellular Markers
- Extracellular Matrix
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/COL7A1
bosterbio.com/bosterbio-gene-info-cards/COL7A1
References
PMID: 8088784 by Christiano A.M., et al. Structural organization of the human type VII collagen gene (COL7A1), composed of more exons than any previously characterized gene.
PMID: 8051117 by Christiano A.M., et al. Cloning of human type VII collagen. Complete primary sequence of the alpha 1(VII) chain and identification of intragenic polymorphisms.
2 Publications of Boster COL7A1 Antibodies & ELISA Kits
- PubMed ID: 10.1038/s41401-021-00782-6, CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice vi...
- PubMed ID: 10.1016/j.biomaterials.2021.121260, An improved osseointegration of metal implants by pitavastatin loaded multilayer...
*More publications can be found for each product on its corresponding product page