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- Table of Contents
Adapter molecule crk Antibodies
AND CRK ELISA kits, Adapter molecule crk Proteins
Many biological assays use antibodies to detect Adapter molecule crk, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Adapter molecule crk in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Adapter molecule crk antibodies...
Designing a Western blot for Adapter molecule crk? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CRK Western Blot GuideCRK Infographic by Boster Bio
All CRK Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IP, IF, ICC, WB
$370
Cat # A02100-1
100 µg/vial
Cat # A02100-1
100 µg/vial
Human, Mouse, Rat
WB
$370
Cat # PA2125-2
100 μg/vial
Cat # PA2125-2
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M02100-2
100 µl/vial
Cat # M02100-2
100 µl/vial
Human, Mouse, Rat
Flow Cytometry, WB
$370
Cat # PA1808
100 μg/vial
Cat # PA1808
100 μg/vial
Human, Mouse, Rat
IHC, ICC, WB
$482
Cat # A00960Y249-1
100ul
Cat # A00960Y249-1
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC1982
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1982
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1142
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1142
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC1983
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC1983
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1143
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1143
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
Flow Cytometry, IP, IF, ICC, WB
$370
Cat # M02533-3
100 μl/vial
Cat # M02533-3
100 μl/vial
Human, Monkey, Mouse, Rat
ELISA, IF, WB
$380
Cat # A02533Y221-1
100ul
Cat # A02533Y221-1
100ul
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A00960Y165
100ul
Cat # A00960Y165
100ul
CRK Overview
Facts about Adapter molecule crk.
Adapter molecule crk (CRK)
Isoform Crk-II: Regulates cell adhesion, spreading and migration. Mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner.
Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. May regulate the EFNA5-EPHA3 signaling.
Gene Information
| Human | |
|---|---|
| Gene Name: | CRK |
| Uniprot: | P46108 |
| Entrez: | 1398 |
Family
| Belongs to: |
|---|
| CRK family |
Alternative Names
adapter molecule crk; avian sarcoma virus CT10 (v-crk) oncogene homolog; Crk; CRKII; p38; Proto-oncogene c-Crk; v-crk avian sarcoma virus CT10 oncogene homolog; v-crk sarcoma virus CT10 oncogene homolog (avian)
Molecular Weight
Mass (kDA):
33.831 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 17p13.3 |
| Sequence: | 17; NC_000017.11 (1420693..1456232, complement) |
Subcellular Localizations
Cytoplasm. Cell membrane. Translocated to the plasma membrane upon cell adhesion.
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Cell Invasion
- Leukemia
- Neoplasm Metastasis
- Myeloid Leukemia
- Myeloid Leukemia, Chronic
- Sarcoma
- Neoplasm Invasiveness
- Malignant Paraganglionic Neoplasm
- Carcinoma
Pathways
- Cell Migration
- Cell Adhesion
- Cell Motility
- Cell Cycle
- Localization
- Cell Proliferation
- Cell Growth
- Rna Interference
- Phagocytosis
- Cell Death
- Pathogenesis
- T Cell Activation
- Endocytosis
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Ribosylation
- Methylation
- Myristoylation
Research Areas
- Apoptosis
- Ovarian Carcinoma Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CRK
bosterbio.com/bosterbio-gene-info-cards/CRK
References
PMID: 1630456 by Matsuda M., et al. Two species of human CRK cDNA encode proteins with distinct biological activities.
PMID: 8378094 by Fioretos T., et al. CRK proto-oncogene maps to human chromosome band 17p13.
3 Publications of Boster Adapter molecule crk Antibodies & ELISA Kits
- PubMed ID: 26822763, Long noncoding RNA NEAT1 promotes laryngeal squamous cell cancer through regulat...
- PubMed ID: 25734831, Ren J, Huang Q, Xu Y, Yang M, Yang J, Hu K. Anticancer Drugs. 2015 Jul;26(6):599...
- PubMed ID: 25431082, Zhou R, Lu Z, Liu K, Guo J, Liu J, Zhou Y, Yang J, Mi M, Xu H. Curr Cancer Drug ...
*More publications can be found for each product on its corresponding product page