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- Table of Contents
CTBP1 Antibodies
AND CTBP1 ELISA kits, CTBP1 Proteins
Many biological assays use antibodies to detect CTBP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CTBP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CTBP1 antibodies...
Designing a Western blot for CTBP1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CTBP1 Western Blot GuideCTBP1 Infographic by Boster Bio
All CTBP1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB9425
100 μg/vial
Cat # PB9425
100 μg/vial
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1570
100 μg/vial
Cat # PA1570
100 μg/vial
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M02123-2
100 μl/vial
Cat # M02123-2
100 μl/vial
Human, Mouse, Rat
ELISA
$540
Cat # EKC2612
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2612
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1147
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1147
1 kit, containing one 96-well plate and all necessary reagents
CTBP1 Overview
Facts about C-terminal-binding protein 1.
C-terminal-binding protein 1 (CTBP1)
Corepressor targeting diverse transcription regulators such as GLIS2 or BCL6. Has dehydrogenase activity.
Involved in controlling the balance between tubular and piled structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation.
Gene Information
| Human | |
|---|---|
| Gene Name: | CTBP1 |
| Uniprot: | Q13363 |
| Entrez: | 1487 |
Family
| Belongs to: |
|---|
| D-isomer specific 2-hydroxyacid dehydrogenase family |
Alternative Names
BARS; brefeldin A-ribosylated substrate; CTBP; CtBP1; C-terminal binding protein 1; C-terminal-binding protein 1; EC 1.1.1; EC 1.1.1.-; EC 1.1.1.158; MGC104684
Molecular Weight
Mass (kDA):
47.535 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4p16.3 |
| Sequence: | 4; NC_000004.12 (1211444..1250355, complement) |
Tissue Specificity
Expressed in germinal center B-cells.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Malignant Neoplasms
- Neoplasms
- Cell Transformation, Neoplastic
- Malignant Neoplasm Of Breast
- Neoplasm Metastasis
- Carcinoma
- Mammary Neoplasms
- Leukemia
- Malignant Tumor Of Colon
- Cell Invasion
- Melanoma
- Neoplasm Invasiveness
Interacting Proteins
- BCAS3
- CBX4
- CDKN2D
- CEP68
- CRY2
- CTBP2
- FOXP2
- HEMGN
- HIC1
- HOXB5
Pathways
- Localization
- Cell Cycle
- Membrane Fission
- Cell Proliferation
- Chromatin Remodeling
- Oncogenesis
- Transport
- Mitosis
- Cell Migration
- Macropinocytosis
- Cell Differentiation
- Dna Repair
- Methylation
PTMs
- Ribosylation
- Acetylation
- Phosphorylation
- Sumoylation
- Methylation
Research Areas
- Cell Cycle and Replication
- Wnt Signaling Pathway
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CTBP1
bosterbio.com/bosterbio-gene-info-cards/CTBP1
References
PMID: 7479821 by Schaeper U., et al. Molecular cloning and characterization of a cellular phosphoprotein that interacts with a conserved C-terminal domain of adenovirus E1A involved in negative modulation of oncogenic transformation.
PMID: 9858600 by Sewalt R.G.A.B., et al. C-terminal binding protein is a transcriptional repressor that interacts with a specific class of vertebrate polycomb proteins.