This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
CD86 Antibodies
AND CD86 ELISA kits, CD86 Proteins
Many biological assays use antibodies to detect CD86, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with CD86 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop CD86 antibodies...
Designing a Western blot for CD86? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the CD86 Western Blot GuideCD86 Infographic by Boster Bio
All CD86 Products
Product
Figures
Specificity
Applications
Price
Anti-Cd86 Antibody Picoband®
21 Citations
Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A00220-4
100 μg/vial
Cat # A00220-4
100 μg/vial
Anti-CD86/B7 2 Rabbit Monoclonal Antibody
42 Citations
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00220-1
100 μl
Cat # M00220-1
100 μl
Anti-CD86 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A00220-3
100 μg/vial
Cat # A00220-3
100 μg/vial
Mouse
ELISA
$499
Cat # EK0711
96 wells/kit, with removable strips.
Cat # EK0711
96 wells/kit, with removable strips.
Mouse
ELISA, IP, IF, IHC, WB
$146
Cat # M00220-5
20μL, 40μL, 100μL, 200μL
Cat # M00220-5
20μL, 40μL, 100μL, 200μL
CD86 Overview
Facts about T-lymphocyte activation antigen CD86.
T-lymphocyte activation antigen CD86 (CD86)
Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 manufacturing, by binding CD28 or CTLA-4. May play a vital role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between resistance and anergy that is made by T- cells within 24 hours after activation.
Isoform 2 interferes with the formation of CD86 clusters, and thus functions as a negative regulator of T-cell activation. .
Gene Information
| Human | |
|---|---|
| Gene Name: | CD86 |
| Uniprot: | P42081 |
| Entrez: | 942 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Activation B7-2 antigen; B70; B7-2 antigen; B72; B7-2; B-lymphocyte activation antigen B7-2; BU63; CD28 antigen ligand 2; CD28LG2B7-2 antigen); CD86 antigen; CD86 molecule; CD86; CTLA-4 counter-receptor B7.2; FUN-1; LAB72; MGC34413; T-lymphocyte activation antigen CD86
Molecular Weight
Mass (kDA):
37.682 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3q13.33 |
| Sequence: | 3; NC_000003.12 (122055362..122121143) |
Tissue Specificity
Expressed by activated B-lymphocytes and monocytes.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein.
Diseases
- Neoplasms
- Malignant Neoplasms
- Inflammation
- Autoimmune Reaction
- Tissue Adhesions
- Autoimmune Diseases
- Leukemia
- Decreased Immunologic Activity [pe]
- Autoimmunity
- Carcinoma
- Infective Disorder
- Asthma
- Hiv Infections
Interacting Proteins
- CTLA4
Pathways
- Immune Response
- Secretion
- Cell Activation
- Cell Proliferation
- Cytokine Production
- T Cell Activation
- T Cell Proliferation
- Pathogenesis
- Sensitization
- Cell Maturation
- Cell Differentiation
- Phagocytosis
- Hypersensitivity
PTMs
- Phosphorylation
- Methylation
- Ubiquitination
- Cleavage
- Glycosylation
- Acetylation
- Reduction
- Ribosylation
- Phosphorothioation
- Biotinylation
Research Areas
- Adaptive Immunity
- Cell Cycle and Replication
- Dendritic Cell Markers
- Diabetes Research
- Immunology
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/CD86
bosterbio.com/bosterbio-gene-info-cards/CD86
References
PMID: 7694153 by Azuma M., et al. B70 antigen is a second ligand for CTLA-4 and CD28.
PMID: 7694363 by Freeman G.J., et al. Cloning of B7-2: a CTLA-4 counter-receptor that costimulates human T cell proliferation.
3 Publications of Boster CD86 Antibodies & ELISA Kits
- PubMed ID: 10.1080/17435390.2018.1425501, Macrophage polarization and activation at the interface of multi-walled carbon n...
- PubMed ID: 10.1016/j.brainresbull.2019.07.019, Lithium chloride promoted hematoma resolution after intracerebral hemorrhage thr...
- PubMed ID: , Near infrared light-triggered on-demand Cur release from Gel-PDA@Cur composite h...
*More publications can be found for each product on its corresponding product page