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- Table of Contents
Dkk1 Antibodies
AND Dkk1 ELISA kits, Dkk1 Proteins
Many biological assays use antibodies to detect Dkk1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Dkk1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Dkk1 antibodies...
Designing a Western blot for Dkk1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the DKK1 Western Blot GuideDkk1 Infographic by Boster Bio
All Dkk1 Products
Product
Figures
Specificity
Applications
Price
Human DKK-1 / Dickkopf 1 ELISA Kit PicoKine®
10 Citations
Human
ELISA
$499
Cat # EK0867
96 wells/kit, with removable strips.
Cat # EK0867
96 wells/kit, with removable strips.
Mouse DKK-1 ELISA Kit PicoKine®
2 Citations
Mouse
ELISA
$499
Cat # EK0925
96 wells/kit, with removable strips.
Cat # EK0925
96 wells/kit, with removable strips.
Human
ELISA
$500
Cat # EZ0867
5 plates/kit
Cat # EZ0867
5 plates/kit
Human
ELISA
$499
Cat # FEK0867
96 wells/kit, with removable strips.
Cat # FEK0867
96 wells/kit, with removable strips.
Mouse
ELISA
$499
Cat # FEK0925
96 wells/kit, with removable strips.
Cat # FEK0925
96 wells/kit, with removable strips.
Anti-DKK1 Rabbit Monoclonal Antibody
1 Citations
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00632
100 μl
Cat # M00632
100 μl
Human, Mouse, Rat
WB
$370
Cat # PA1462
100 μg/vial
Cat # PA1462
100 μg/vial
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00632-3
100 μg
Cat # M00632-3
100 μg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00632-2
100 μg
Cat # M00632-2
100 μg
Human, Rat
Flow Cytometry, IF, IHC, ICC, WB
$405
Cat # A00632-2
100ul
Cat # A00632-2
100ul
Dkk1 Overview
Facts about Dickkopf-related protein 1.
Dickkopf-related protein 1 (Dkk1)
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6 (PubMed:18524778). Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity (PubMed:26206087).
Plays a role in limb development; attenuates Wnt signaling in the developing limb to permit normal limb patterning (PubMed:18505822). .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Dkk1 |
| Uniprot: | O54908 |
| Entrez: | 13380 |
Family
| Belongs to: |
|---|
| dickkopf family |
Alternative Names
dickkopf (Xenopus laevis) homolog 1; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; Dickkopf-1; dickkopf-related protein 1; Dkk1; Dkk-1; hDkk-1; SKdickkopf-1 like
Molecular Weight
Mass (kDA):
29.298 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 19|19 C1 |
| Sequence: | 19; |
Diseases
- Malignant Neoplasms
- Neoplasms
- Multiple Myeloma
- Osteoporosis
- Bone Diseases
- Carcinoma
- Neoplasm Metastasis
- Cell Transformation, Neoplastic
- Osteopenia
- Fracture
- Malignant Neoplasm Of Breast
- Arthritis
Pathways
- Cell Proliferation
- Osteoblast Differentiation
- Pathogenesis
- Bone Resorption
- Cell Growth
- Secretion
- Regeneration
- Methylation
- Cell Death
- Bone Remodeling
- Cell Cycle
- Localization
- Cell Differentiation
PTMs
- Phosphorylation
- Methylation
- Glycosylation
- Demethylation
- Cleavage
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Dkk1
bosterbio.com/bosterbio-gene-info-cards/Dkk1
References
PMID: 9450748 by Glinka A., et al. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction.
PMID: 17143291 by Niehrs C.; Function and biological roles of the Dickkopf family of Wnt modulators.
11 Publications of Boster Dkk1 Antibodies & ELISA Kits
- PubMed ID: PMID:27821026, DKK1 in relation to HCV induced liver cirrhosis and HCV induced HCC curative res...
- PubMed ID: 10.1155/2017/6861575, Dickkopf-1 Is a Biomarker for Systemic Lupus Erythematosus and Active Lupus Neph...
- PubMed ID: 10.1097/MD.0000000000025112, Serum midkine is a more sensitive predictor for hepatocellular carcinoma than Di...
- PubMed ID: 10.1016/j.apjtm.2017.03.016, Combination of serum tumor markers dickkopf-1, DCP and AFP for the diagnosis of ...
- PubMed ID: 10.1007/s00404-019-05126-8, Wnt signaling pathway in early- and late-onset preeclampsia: evaluation with Dic...
- PubMed ID: 33907088, El-Shayeb AF,El-Habachi NM,Mansour AR,Zaghloul MS.Serum midkine is a more sensit...
- PubMed ID: 33795652, Qi L,Chen J,Zhou B,Xu K,Wang K,Fang Z,Shao Y,Yuan Y,Zheng S,Hu W.HomeoboxC6 prom...
- PubMed ID: -, Huo Q,Xu C,Shao Y,Yu Q,Huang L,Liu Y,Bao H.Free CA125 promotes ovarian cancer ce...
- PubMed ID: 27821026, DKK1 in relation to HCV induced liver cirrhosis and HCV induced HCC curative res...
- PubMed ID: 28552111 , Combination of serum tumor markers dickkopf-1, DCP and AFP for the diagnosis of ...
- PubMed ID: 26189760, SIRT6 Deficiency Culminates in Low-Turnover Osteopenia
*More publications can be found for each product on its corresponding product page