EIF6 Antibodies

AND EIF6 ELISA kits, EIF6 Proteins

Many biological assays use antibodies to detect EIF6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF6 antibodies...

We validate the specificity of these antibodies to EIF6 by testing them on tissues known to express EIF6 positively and negatively. Browse below to find the EIF6 antibody that suites your experiment. We have 16 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing a Western blot for EIF6? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.

Open the EIF6 Western Blot Guide

EIF6 Infographic by Boster Bio

All EIF6 Products

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Specificity

Applications

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Anti-DDX1 Picoband® Antibody (monoclonal, 3I10)

Western blot analysis of DDX1 using anti-DDX1 antibody (M03727)

IHC analysis of DDX1 using anti-DDX1 antibody (M03727)

+10

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03727
100 μg/vial

Anti-NKCC1/SLC12A2 Antibody Picoband® (monoclonal, 6G7D2)

1 Citations

Western blot analysis of NKCC1/SLC12A2 using anti-NKCC1/SLC12A2 antibody (M03603)

IHC analysis of NKCC1/SLC12A2 using anti-NKCC1/SLC12A2 antibody (M03603)

Human, Mouse, Rat

IF, IHC, WB

$370
Cat # M03603
100 μg/vial

Anti-integrin beta 4 binding protein/EIF6 Antibody Picoband®

1 Citations

IHC analysis of EIF6 using anti-EIF6 antibody (PB9582)

Human, Mouse, Rat

IHC, ICC, WB

$370
Cat # PB9582
100 μg/vial

Anti-PDIA6 Antibody Picoband® (monoclonal, 3H5E7)

Western blot analysis of PDIA6 using anti-PDIA6 antibody (M03813-1)

IHC analysis of PDIA6 using anti-PDIA6 antibody (M03813-1)

Human, Monkey

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03813-1
100 μg/vial

Anti-U2AF65/U2AF2 Picoband® Antibody (monoclonal, 3G9)

Western blot analysis of U2AF65/U2AF2 using anti-U2AF65/U2AF2 antibody (M03639-1)

IHC analysis of U2AF65/U2AF2 using anti U2AF65/U2AF2 antibody (M03639-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03639-1
100 μg/vial

Anti-U2AF65/U2AF2 Picoband® Antibody (monoclonal, 10F4)

Western blot analysis of U2AF65/U2AF2 using anti-U2AF65/U2AF2 antibody (M03639)

IHC analysis of U2AF65/U2AF2 using anti U2AF65/U2AF2 antibody (M03639)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03639
100 μg/vial

Anti-CD20 Antibody Picoband® (monoclonal, 4D11)

1 Citations

Western blot analysis of CD20 using anti-CD20 antibody (M03780-5)

IHC analysis of CD20 using anti-CD20 antibody (M03780-5)

Human

IF, IHC, WB

$370
Cat # M03780-5
100 μg/vial

Anti-DDX1 Picoband® Antibody (monoclonal, 11E5)

Western blot analysis of DDX1 using anti-DDX1 antibody (M03727-2)

IHC analysis of DDX1 using anti-DDX1 antibody (M03727-2)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M03727-2
100 μg/vial

Anti-Annexin VI Antibody Picoband® (monoclonal, 4C4)

Western blot analysis of Annexin VI using anti-Annexin VI antibody (M03735-1)

IHC analysis of Annexin VI using anti-Annexin VI antibody (M03735-1)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03735-1
100 μg/vial

Anti-CD20/MS4A1 Antibody Picoband® (monoclonal, 4I11)

1 Citations

IF analysis of CD20/MS4A1 using anti-CD20/MS4A1 antibody (M03780-4)

Western blot analysis of CD20/MS4A1 using anti-CD20/MS4A1 antibody (M03780-4)

Human

IF, WB

$370
Cat # M03780-4
100 μg/vial

Anti-EIF6 Antibody Picoband® (monoclonal, 2I11)

Western blot analysis of EIF6 using anti-EIF6 antibody (M03581)

IHC analysis of EIF6 using anti-EIF6 antibody (M03581)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M03581
100 μg/vial

Anti-DDX1 Picoband® Antibody (monoclonal, 2D4)

Western blot analysis of DDX1 using anti-DDX1 antibody (M03727-1)

IHC analysis of DDX1 using anti-DDX1 antibody (M03727-1)

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$370
Cat # M03727-1
100 μg/vial

Anti-MCM5 Picoband® Antibody (monoclonal, 4G10)

IHC analysis of MCM5 using anti-MCM5 antibody (M03642-2)

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M03642-2
100 μg/vial

Anti-integrin beta 4 binding protein/EIF6 Antibody Picoband®

Anti-EIF6 antibody, PA2031, Western blottingLane 1: Rat Liver Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: COLO320 Cell LysateLane 4: SW620 Cell LysateLane 5: HELA Cell LysateLane 6: 293T Cell Lysate
Lane 7: HEPA Cell Lysate

Anti-EIF6 antibody, PA2031, IHC(P)IHC(P): Human Intestinal Cancer Tissue

Anti-EIF6 antibody, PA2031, IHC(F)IHC(F): Human Placenta Tissue

Human, Mouse, Rat

IHC, WB

$370
Cat # PA2031
100 μg/vial

Integrin beta 4 binding protein (EIF6) (NM_181468) Human Over-expression Lysate

Human

$628
Cat # LS003692
20 µg, 100 µg

Integrin beta 4 binding protein (EIF6) (NM_181468) Human Recombinant Protein

Coomassie blue staining of purified EIF6 protein

$1062
Cat # PROTP56537
20 µg

EIF6 Overview

Facts about Eukaryotic translation initiation factor 6.

EIF6 3D structure. Source: alphafold

Eukaryotic translation initiation factor 6 (EIF6)

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex from the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors.

Is also involved in ribosome biogenesis. Associates with pre-60S subunits from the nucleus and is involved in its nuclear export.

Gene Information

Human
Gene Name:	EIF6
Uniprot:	P56537
Entrez:	3692

Family

Belongs to:

eIF-6 family

Alternative Names

B(2)GCN homolog; b(2)gcn; B4 integrin interactor; CAB; EIF3Ap27(BBP); eIF-6; eukaryotic translation initiation factor 3A; eukaryotic translation initiation factor 6; ITGB4BPintegrin beta 4 binding protein; p27 beta-4 integrin-binding protein; p27BBP

Molecular Weight

Mass (kDA):
26.599 kDA

Genomic Context


Human

Location:	20q11.22
Sequence:	20; NC_000020.11 (35278906..35284772, complement)

Tissue Specificity

Expressed at very high levels in colon carcinoma with lower levels in normal colon and ileum and lowest levels in kidney and muscle (at protein level).

Subcellular Localizations

Cytoplasm. Nucleus, nucleolus. Shuttles between cytoplasm and nucleus/nucleolus.

Diseases

Malignant Neoplasms
Neoplasms
Shwachman Syndrome
Exocrine Pancreatic Insufficiency
Carcinoma
Bone Marrow Diseases
Lipomatosis
Cell Transformation, Neoplastic
Leukemia
Ovarian Neoplasm
Adenocarcinoma
Tissue Adhesions
Neoplasm Metastasis

Pancytopenia
Lymphoma
Malignant Neoplasm Of Lung
Malignant Neoplasm Of Ovary
White Spots, Dental
Cell Invasion
Malignant Squamous Cell Neoplasm

Interacting Proteins

DHX58
EIF2AK2
NREP
OAS3
Prkcb

Pathways

Translation
Ribosome Biogenesis
Localization
Ribosome Assembly
Cell Growth
Cell Cycle
Cell Differentiation
Nuclear Export
Cell Adhesion
Cell Migration
Eye Development
Cell Proliferation
Cell Death

Pathogenesis
Protein Phosphorylation
Gene Silencing
Fertilization
Hypersensitivity
Pronephros Formation
Pronephros Development

PTMs

Phosphorylation

Nitration

Dephosphorylation

Research Areas

Core ESC-Like Genes
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF6

References

PMID: 9405604 by Si K., et al. Molecular cloning and functional expression of a human cDNA encoding translation initiation factor 6.

PMID: 9374518 by Biffo S., et al. Isolation of a novel beta4 integrin-binding protein (p27(BBP)) highly expressed in epithelial cells.