This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Protocadherin Fat 1 Antibodies
AND FAT1 ELISA kits, Protocadherin Fat 1 Proteins
Many biological assays use antibodies to detect Protocadherin Fat 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protocadherin Fat 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protocadherin Fat 1 antibodies...
Designing an IHC experiment for Protocadherin Fat 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the FAT1 IHC GuideFAT1 Infographic by Boster Bio
All FAT1 Products
Product
Figures
Specificity
Applications
Price
Anti-Ubiquitin D UBD Rabbit Monoclonal Antibody
1 Citations
Human, Mouse
IF, IHC, ICC, WB
$370
Cat # M01970
100 μl
Cat # M01970
100 μl
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01975
100 μl
Cat # M01975
100 μl
FAT1 Overview
Facts about Protocadherin Fat 1.
Protocadherin Fat 1 (FAT1)
Plays an important role for cellular polarization, directed cell migration and regulating cell-cell contact. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | FAT1 |
| Uniprot: | Q14517 |
| Entrez: | 2195 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FAT tumor suppressor 1; FAT tumor suppressor homolog 1 (Drosophila)
Molecular Weight
Mass (kDA):
506.273 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q35.2 |
| Sequence: | 4; NC_000004.12 (186587789..186726696, complement) |
Tissue Specificity
Expressed in many epithelial and some endothelial and smooth muscle cells.
Subcellular Localizations
Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, perinuclear region.
Diseases
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Carcinoma
- Cell Invasion
- Malignant Neoplasm Of Breast
- Neoplasm Invasiveness
- Nervousness
- Kidney Diseases
- Malignant Neoplasm Of Mouth
- Colorectal Cancer
- Malignant Neoplasm Of Pancreas
- Bipolar Disorder
Interacting Proteins
- ENAH
- HOMER3
- Homer3
Pathways
- Localization
- Transport
- Cell Growth
- Fatty Acid Transport
- Cell Adhesion
- Cell-cell Adhesion
- Cell Proliferation
- Cell Migration
- Cytokinesis
- Pathogenesis
- Glomerular Filtration
- Cell Death
- Cell Division
PTMs
- Phosphorylation
- Cleavage
- Oxidation
- Methylation
Research Areas
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FAT1
bosterbio.com/bosterbio-gene-info-cards/FAT1
References
PMID: 8586420 by Dunne J., et al. Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule.
PMID: 15922730 by Magg T., et al. Processing of the human protocadherin Fat1 and translocation of its cytoplasmic domain to the nucleus.
3 Publications of Boster Protocadherin Fat 1 Antibodies & ELISA Kits
- PubMed ID: 30745528, Hu H,Xue J,Dong R,Zhao Y,Song C,Zhao H,Hescheler J,Zhang Y,Liang H.STAT3 Phospho...
- PubMed ID: 30745528, STAT3 Phosphorylation Mediating DMSO's Function on Fetal Cardiomyocyte Prolifera...
- PubMed ID: 25523932, Xu Lx, Li Zh, Tao Yf, Li Rh, Fang F, Zhao H, Li G, Li Yh, Wang J, Feng X, Pan J....
*More publications can be found for each product on its corresponding product page