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- Table of Contents
Fibrinogen beta chain Antibodies
AND FGB ELISA kits, Fibrinogen beta chain Proteins
Many biological assays use antibodies to detect Fibrinogen beta chain, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fibrinogen beta chain in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fibrinogen beta chain antibodies...
Designing a Western blot for Fibrinogen beta chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the FGB Western Blot GuideFGB Infographic by Boster Bio
All FGB Products
Product
Figures
Specificity
Applications
Price
Human
IHC, WB
$370
Cat # M01204-1
100 μg/vial
Cat # M01204-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A01204-1
100 μg/vial
Cat # A01204-1
100 μg/vial
Human
$628
Cat # LS002244
20 µg, 100 µg
Cat # LS002244
20 µg, 100 µg
FGB Overview
Facts about Fibrinogen beta chain.
Fibrinogen beta chain (FGB)
Cleaved by the protease thrombin to yield monomers that, together with fibrinogen alpha (FGA) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a significant function in hemostasis among the principal elements of blood clots.
In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood.
Gene Information
| Human | |
|---|---|
| Gene Name: | FGB |
| Uniprot: | P02675 |
| Entrez: | 2244 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Beta-Fibrinogen; FGB Peptide; FIBB; Fibrinogen beta chain; Fibrinogen Type II; fibrinogen, B beta polypeptide; Fibrinopeptide B; FPB; MGC104327; MGC120405
Molecular Weight
Mass (kDA):
55.928 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q31.3 |
| Sequence: | 4; NC_000004.12 (154562980..154572807) |
Tissue Specificity
Detected in blood plasma (at protein level).
Subcellular Localizations
Secreted.
Diseases
- Afibrinogenemia
- Hereditary Factor I Deficiency Disease
- Infarction
- Cardiovascular Diseases
- Myocardial Infarction
- Hemorrhage
- Inflammation
- Cerebrovascular Accident
- Hypofibrinogenemia
- Blood Coagulation Disorders
- Dysfibrinogenemia
- Thrombosis
- 5,10-methylenetetrahydrofolate Reductase Deficiency
Pathways
- Coagulation
- Secretion
- Hemostasis
- Pathogenesis
- Mrna Splicing
- Inflammatory Response
- Translation
- Fibrinolysis
- Mrna Processing
- Meiosis
- Fertilization
- Complement Activation
- Chromosome Segregation
PTMs
Research Areas
- Cell Cycle and Replication
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FGB
bosterbio.com/bosterbio-gene-info-cards/FGB
References
PMID: 6688356 by Chung D.W., et al. Characterization of complementary deoxyribonucleic acid and genomic deoxyribonucleic acid for the beta chain of human fibrinogen.
PMID: 2102623 by Chung D.W., et al. Nucleotide sequences of the three genes coding for human fibrinogen.