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- Table of Contents
HEXA Antibodies
AND HEXA ELISA kits, HEXA Proteins
Many biological assays use antibodies to detect HEXA, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HEXA in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HEXA antibodies...
Designing a Western blot for HEXA? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the HEXA Western Blot GuideHEXA Infographic by Boster Bio
All HEXA Products
Product
Figures
Specificity
Applications
Price
Anti-Fox2/RBM9/RBFOX2 Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, IF, IHC, ICC, WB
$370
Cat # A05389-1
100 μg/vial
Cat # A05389-1
100 μg/vial
Human HEXA ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK2215
96 wells/kit, with removable strips.
Cat # EK2215
96 wells/kit, with removable strips.
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, WB
$370
Cat # A05389-2
100 µg/vial
Cat # A05389-2
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A05402-3
100 μg/vial
Cat # A05402-3
100 μg/vial
Human
$628
Cat # LS051447
20 µg, 100 µg
Cat # LS051447
20 µg, 100 µg
HEXA Overview
Facts about Beta-hexosaminidase subunit alpha.
Beta-hexosaminidase subunit alpha (HEXA)
Responsible for the degradation of GM2 gangliosides, and a number of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides.
The form S has no measurable activity. .
Gene Information
| Human | |
|---|---|
| Gene Name: | HEXA |
| Uniprot: | P06865 |
| Entrez: | 3073 |
Family
| Belongs to: |
|---|
| glycosyl hydrolase 20 family |
Alternative Names
beta-hexosaminidase subunit alpha; Beta-N-acetylhexosaminidase subunit alpha; EC 3.2.1; EC 3.2.1.52; HEXA; hexosaminidase A (alpha polypeptide); Hexosaminidase A; Hexosaminidase subunit A; MGC99608; N-acetyl-beta-glucosaminidase subunit alpha; TSD
Molecular Weight
Mass (kDA):
60.703 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 15q23 |
| Sequence: | 15; NC_000015.10 (72340924..72376014, complement) |
Subcellular Localizations
Lysosome.
Diseases
- Tay-sachs Disease
- Gangliosidoses
- Gangliosidoses, Gm2
- Hepatitis B
- Hepatitis
- Influenza
- Sandhoff Disease
- Neurodegenerative Disorders
- Tetanus
- Diphtheria
- Pertussis
- Poliomyelitis
- Lysosomal Storage Diseases
Interacting Proteins
- HEXB
Pathways
- Secretion
- Immune Response
- Mismatch Repair
- Pathogenesis
- Localization
- Excretion
- Transport
- Virulence
- Aging
- Bone Resorption
- Cell Adhesion
- Cell Proliferation
- Dna Repair
PTMs
- Cleavage
- Methylation
- Phosphorylation
- Nitration
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HEXA
bosterbio.com/bosterbio-gene-info-cards/HEXA
References
PMID: 2933746 by Myerowitz R., et al. Human beta-hexosaminidase alpha chain: coding sequence and homology with the beta chain.
PMID: 2952641 by Proia R.L., et al. Organization of the gene encoding the human beta-hexosaminidase alpha-chain.