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- Table of Contents
HMGB2 Antibodies
AND HMGB2 ELISA kits, HMGB2 Proteins
Many biological assays use antibodies to detect HMGB2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with HMGB2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop HMGB2 antibodies...
Designing an IHC experiment for HMGB2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the HMGB2 IHC GuideHMGB2 Infographic by Boster Bio
All HMGB2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # PB10002
100 μg/vial
Cat # PB10002
100 μg/vial
Human
Cell Culture
$77
Cat # PROTP26583-3
5ug,20ug,100ug
Cat # PROTP26583-3
5ug,20ug,100ug
Human
Cell Culture
$77
Cat # PROTP26583-2
5ug,20ug,100ug
Cat # PROTP26583-2
5ug,20ug,100ug
HMGB2 Overview
Facts about High mobility group protein B2.
High mobility group protein B2 (HMGB2)
Multifunctional protein with numerous functions in different cellular compartments. May act in a redox sensitive manner.
From the nucleus is an abundant chromatin-associated non-histone protein involved in transcription, chromatin remodeling and V(D)J recombination and likely other processes. Binds DNA with a preference to non-canonical DNA structures like single-stranded DNA.
Gene Information
| Human | |
|---|---|
| Gene Name: | HMGB2 |
| Uniprot: | P26583 |
| Entrez: | 3148 |
Family
| Belongs to: |
|---|
| HMGB family |
Alternative Names
High mobility group protein 2; high mobility group protein B2; high-mobility group box 2; HMG-2; HMG2high-mobility group (nonhistone chromosomal) protein 2
Molecular Weight
Mass (kDA):
24.034 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q34.1 |
| Sequence: | 4; NC_000004.12 (173331376..173334358, complement) |
Tissue Specificity
Expressed in gastric and intestinal tissues (at protein level).
Subcellular Localizations
Nucleus. Chromosome. Cytoplasm. Secreted. In basal state predominantly nuclear.
Diseases
- Neoplasms
- Malignant Neoplasms
- Carcinoma
- Inflammation
- Degenerative Polyarthritis
- Muscular Dystrophy, Facioscapulohumeral
- Malignant Paraganglionic Neoplasm
- Hypertrophy
- Ulcerative Colitis
- Epithelial Ovarian Cancer
- Ovarian Neoplasm
- Dystrophy
- Cell Transformation, Neoplastic
Pathways
- Cell Death
- Cell Cycle
- V(d)j Recombination
- Localization
- Cell Proliferation
- Dna Repair
- Cell Differentiation
- Chromatin Remodeling
- Nucleosome Assembly
- Aging
- Mitosis
- Cell Adhesion
- Transposition
PTMs
- Cleavage
- Phosphorylation
Research Areas
- Cell Cycle and Replication
- Core ESC-Like Genes
- Stem Cell Markers
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/HMGB2
bosterbio.com/bosterbio-gene-info-cards/HMGB2
References
PMID: 1754403 by Majumdar A., et al. Sequence of human HMG2 cDNA.
PMID: 1551873 by Shirakawa H., et al. Structure of a gene coding for human HMG2 protein.