Homeobox protein HMX3 Antibodies

AND Hmx3 ELISA kits, Homeobox protein HMX3 Proteins

Many biological assays use antibodies to detect Homeobox protein HMX3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Homeobox protein HMX3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Homeobox protein HMX3 antibodies...

We validate the specificity of these antibodies to Homeobox protein HMX3 by testing them on tissues known to express Hmx3 positively and negatively. Browse below to find the Hmx3 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Hmx3 Infographic by Boster Bio

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Hmx3 Overview

Facts about Homeobox protein HMX3.

Homeobox protein HMX3 (Hmx3)

Transcription factor involved in specification of neuronal cell types and that is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence.

Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.

Gene Information

Mouse
Gene Name:	Hmx3
Uniprot:	P42581
Entrez:	15373

Family

Belongs to:

HMX homeobox family

Alternative Names

H6 family homeobox 3; homeo box (H6 family) 3; homeobox (H6 family) 3; Homeobox protein H6 family member 3; homeobox protein HMX3; Homeobox protein Nkx-5.1; NKX5.1; NKX-5.1; NKX5-1

Molecular Weight

Mass (kDA):
37.859 kDA

Genomic Context


Mouse

Location:	7 F3\|7 74.32 cM
Sequence:	7;

Tissue Specificity

Expressed in the developing CNS, including a specific expression in vestibular structures throughout inner ear development.

Diseases

Nervousness
Macule
Circling Gait
Hyperplasia
Congenital Absence
Exencephaly
Salivary Gland Diseases
Craniofacial Abnormalities
Crest Syndrome
Eye Abnormalities

Diverticulum
Sensorineural Hearing Loss (disorder)
Aplasia, Nos
Misplaced Ear

Pathways

Inner Ear Development
Ear Development
Cell Proliferation
Organ Development
Inner Ear Morphogenesis
Ear Morphogenesis
System Development
Semicircular Canal Formation
Sensory Organ Development
Cell Death
Nervous System Development
Central Nervous System Development
Cell Migration

Cristae Formation
Cell Fate Determination
Lateral Line Development
Cell Fate Specification
Axon Guidance
Cell Differentiation
Regionalization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Hmx3

References

PMID: 7510254 by Bober E., et al. A novel NK-related mouse homeobox gene: expression in central and peripheral nervous structures during embryonic development.

PMID: 10543441 by Mennerich D., et al. Two highly related homeodomain proteins, Nkx5-1 and Nkx5-2, display different DNA binding specificities.