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- Table of Contents
Inverted formin-2 Antibodies
AND INF2 ELISA kits, Inverted formin-2 Proteins
Many biological assays use antibodies to detect Inverted formin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Inverted formin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Inverted formin-2 antibodies...
Designing a Western blot for Inverted formin-2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the INF2 Western Blot GuideDesigning an IHC experiment for Inverted formin-2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the INF2 IHC GuideINF2 Infographic by Boster Bio
All INF2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, IP, IF, IHC, ICC, WB
$370
Cat # A02710-2
100 μg/vial
Cat # A02710-2
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A02710-1
100 μg/vial
Cat # A02710-1
100 μg/vial
INF2 Overview
Facts about Inverted formin-2.
Inverted formin-2 (INF2)
Severs actin filaments and hastens their polymerization and depolymerization. .
.
Gene Information
| Human | |
|---|---|
| Gene Name: | INF2 |
| Uniprot: | Q27J81 |
| Entrez: | 64423 |
Family
| Belongs to: |
|---|
| formin homology family |
Alternative Names
C14orf151; C14orf173DKFZp762A0214; chromosome 14 open reading frame 151; chromosome 14 open reading frame 173; FLJ22056; FSGS5; HBEAG-binding protein 2 binding protein C; HBEBP2-binding protein C; inverted formin, FH2 and WH2 domain containing; inverted formin-2; MGC13251; pp9484
Molecular Weight
Mass (kDA):
135.624 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 14q32.33 |
| Sequence: | 14; NC_000014.9 (104689606..104722535) |
Tissue Specificity
Widely expressed. In the kidney, expression is apparent in podocytes and some tubule cells.
Subcellular Localizations
Cytoplasm, perinuclear region.
Diseases
- Segmental Glomerulosclerosis
- Glomerulosclerosis (disorder)
- Focal Glomerulosclerosis
- Kidney Diseases
- Nephrotic Syndrome
- Kidney Failure, Chronic
- Charcot-marie-tooth Disease
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Adenocarcinoma
- Malignant Neoplasm Of Lung
Pathways
- Sulfate Reduction
- Fermentation
- Methanogenesis
- Photosynthesis
- Localization
- Cell Growth
- Transport
- Cell Adhesion
- Sulfur Oxidation
- Ammonia Oxidation
- Transcytosis
- Nitrogen Fixation
- Demethylation
PTMs
- Oxidation
- Nitration
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/INF2
bosterbio.com/bosterbio-gene-info-cards/INF2
References
PMID: 20023659 by Brown E.J., et al. Mutations in the formin gene INF2 cause focal segmental glomerulosclerosis.
PMID: 21258034 by Boyer O., et al. Mutations in INF2 are a major cause of autosomal dominant focal segmental glomerulosclerosis.