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16 Q&As
Facts about Interleukin-31.
Activates STAT3 and possibly STAT1 and STAT5 Throughout the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896).
May function in skin immunity (PubMed:15184896).Enhances myeloid progenitor cell survival in vitro (PubMed:17379091). Induces RETNLA and serum amyloid A protein expression in macrophages (PubMed:25847241).
| Mouse | |
|---|---|
| Gene Name: | Il31 |
| Uniprot: | Q6EAL8 |
| Entrez: | 76399 |

| Belongs to: |
|---|
| No superfamily |

IL31; IL-31; IL-31interleukin-31; interleukin 31
Mass (kDA):
18.12 kDA

| Mouse | |
|---|---|
| Location: | 5|5 F |
| Sequence: | 5; |




PMID: 15184896 by Dillon S.R., et al. Interleukin 31, a cytokine produced by activated T cells, induces dermatitis in mice.
PMID: 17379091 by Broxmeyer H.E., et al. Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31.
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