This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
14 Citations 6 Q&As
24 Citations 11 Q&As
Facts about Interleukin-5.
Human | |
---|---|
Gene Name: | IL5 |
Uniprot: | P05113 |
Entrez: | 3567 |
Belongs to: |
---|
IL-5 family |
BCDF mu; B-cell differentiation factor I; BCGFII; EDF; Eo-CSF; Eosinophil differentiation factor; IL5; IL-5; IL-5T-cell replacing factor; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; TRF; TRFB cell differentiation factor I
Mass (kDA):
15.238 kDA
Human | |
---|---|
Location: | 5q31.1 |
Sequence: | 5; NC_000005.10 (132539194..132556864, complement) |
Secreted.
Before you apply Boster Bio: Best Uses of the I-Localization IL5 Marker, it is important to know what the product does. This primary antibody of high affinity can recognize IL5 in addition to other ILs in your sample. Because it is highly-affinity, it can detect more ILs than any other primary antibodies. It is used often in immunoassays for studying cellular interactions.
The IL5 marker is one of the most commonly used markers of immune response has been the subject to numerous research studies. Boster Bio has developed a array of tools to aid in making IL5 detection easy and fast. IL5 markers are a crucial component of the immune reaction to various pathogens and viral infections. This antibody is highly specific for IL5 proteins and has numerous beneficial applications in the field of immunology.
The Boster Bio IL5 Marker is an assay kit that tests an IL-4-specific molecule. The human five chromosomes contain the gene called IL-4. Recombinant human IL-4 is the standard product of the kit. It is an unimeric protein that has a molecular weight of 14KDa. The kit comes with the antibodies needed to conduct the assay.
The affinity of a primary antibody is its capacity to bind an antigen. It is a non-covalent, reversible interaction between an antigen (IgG) monoclonal antibodies and its immunoglobulin G. The affinity is measured by the equilibrium dissociation constant (KD) which is proportional to the concentrations of the reactants. A high affinity antibody binds to more antigens over a shorter time.
The activation of B cells is controlled by the IgD class BCR for IgD class. If cells do not have this protein, they create autoantibodies which attack DNA and other nuclear structures. These antibodies are the cause of the development of autoimmune diseases. These mice are more susceptible to autoimmunity because they have high levels of anti-dsDNAIgG antibodies at their early years.
PMID: 3024129 by Azuma C., et al. Cloning of cDNA for human T-cell replacing factor (interleukin-5) and comparison with the murine homologue.
PMID: 2824500 by Tanabe T., et al. Molecular cloning and structure of the human interleukin-5 gene.
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page