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- Table of Contents
1 Citations 16 Q&As
5 Citations 16 Q&As
2 Citations 5 Q&As
3 Citations
Facts about Krueppel-like factor 4.
Binds to the promoter region of its gene and can activate its transcription. Regulates the expression of key transcription factors during embryonic development.
| Human | |
|---|---|
| Gene Name: | KLF4 |
| Uniprot: | O43474 |
| Entrez: | 9314 |

| Belongs to: |
|---|
| krueppel C2H2-type zinc-finger protein family |

Epithelial zinc finger protein EZF; EZF; EZFendothelial Kruppel-like zinc finger protein; GKLFKrueppel-like factor 4; Gut-enriched krueppel-like factor; KLF4; Kruppel-like factor 4 (gut)
Mass (kDA):
54.671 kDA

| Human | |
|---|---|
| Location: | 9q31.2 |
| Sequence: | 9; NC_000009.12 (107484852..107489769, complement) |
Nucleus.





PMID: 9422764 by Yet S.-F., et al. Human EZF, a Kruppel-like zinc finger protein, is expressed in vascular endothelial cells and contains transcriptional activation and repression domains.
PMID: 10392904 by Foster K.W., et al. Oncogene expression cloning by retroviral transduction of adenovirus E1A-immortalized rat kidney RK3E cells: transformation of a host with epithelial features by c-MYC and the zinc finger protein GKLF.
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