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- Table of Contents
LRP1 Antibodies
AND LRP1 ELISA kits, LRP1 Proteins
Many biological assays use antibodies to detect LRP1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with LRP1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop LRP1 antibodies...
Designing an IHC experiment for LRP1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the LRP1 IHC GuideLRP1 Infographic by Boster Bio
All LRP1 Products
Product
Figures
Specificity
Applications
Price
Anti-Acid phosphatase/ACP5 Antibody Picoband®
3 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03277-1
100 μg/vial
Cat # A03277-1
100 μg/vial
Anti-LRPPRC/GP130 Antibody Picoband®
2 Citations
Human, Monkey, Mouse, Rat
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A03264
100 μg/vial
Cat # A03264
100 μg/vial
Human, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A03270-2
100 μg/vial
Cat # A03270-2
100 μg/vial
Anti-PDIP/PDIA2 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, WB
$370
Cat # A03275-1
100 μg/vial
Cat # A03275-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M00829
100 μl
Cat # M00829
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00829-1
20μL, 40μL, 100μL, 200μL
Cat # M00829-1
20μL, 40μL, 100μL, 200μL
Low density lipoprotein receptor related protein 10 (LRP10) (NM_014045) Human Over-expression Lysate
Human
$960
Cat # LS026020
20 µg, 100 µg
Cat # LS026020
20 µg, 100 µg
LRP1 Overview
Facts about Prolow-density lipoprotein receptor-related protein 1.
Prolow-density lipoprotein receptor-related protein 1 (LRP1)
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development.
Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and triggered LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors.
Gene Information
| Human | |
|---|---|
| Gene Name: | LRP1 |
| Uniprot: | Q07954 |
| Entrez: | 4035 |
Family
| Belongs to: |
|---|
| LDLR family |
Alternative Names
A2MR; Alpha-2-Macroglobulin Receptor; APOER; Apolipoprotein E receptor; APR; CD91 antigen; CD91; EC 1.1.1.94; EC 3.4.21.9; IGFBP3R; low density lipoprotein receptor-related protein 1; LRP; LRP-1; LRP1A; prolow-density lipoprotein receptor-related protein 1; TbetaR-V/LRP-1/IGFBP-3 receptor; TGFBR5; type V tgf-beta receptor
Molecular Weight
Mass (kDA):
504.606 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q13.3 |
| Sequence: | 12; NC_000012.12 (57128401..57213377) |
Tissue Specificity
Most abundant in liver, brain and lung.
Subcellular Localizations
[Low-density lipoprotein receptor-related protein 1 85 kDa subunit]: Cell membrane; Single-pass type I membrane protein. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 515 kDa subunit]: Cell membrane; Peripheral membrane protein; Extracellular side. Membrane, coated pit.; [Low-density lipoprotein receptor-related protein 1 intracellular domain]: Cytoplasm. Nucleus. After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus.; Postsynaptic Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center. Localizes to
Diseases
- Alzheimer's Disease
- Neoplasms
- Atherosclerosis
- Malignant Neoplasms
- Inflammation
- Nervousness
- Tissue Adhesions
- Neurodegenerative Disorders
- Cell Invasion
- Nerve Degeneration
- Dementia
- Diabetes Mellitus
- Carcinoma
Interacting Proteins
- APBB1
- APOE
- DLG4
- FCN2
- GRIN2A
- Jag1
- LRPAP1
- MBL2
- Thbs2
Pathways
- Endocytosis
- Transport
- Pathogenesis
- Cell Migration
- Cell Death
- Secretion
- Immune Response
- Transcytosis
- Localization
- Cell Proliferation
- Phagocytosis
- Angiogenesis
- Rna Interference
PTMs
- Phosphorylation
- Cleavage
- Biotinylation
- Glycosylation
- Oxidation
- Carboxylation
- Reduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/LRP1
bosterbio.com/bosterbio-gene-info-cards/LRP1
References
PMID: 3266596 by Herz J., et al. Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor.
PMID: 7534747 by Van Leuven F., et al. Structure of the gene (LRP1) coding for the human alpha 2- macroglobulin receptor lipoprotein receptor-related protein.
3 Publications of Boster LRP1 Antibodies & ELISA Kits
- PubMed ID: 10.1111/odi.13169, JAK2‐STAT3 signaling pathway is involved in rat periapical lesions induced by ...
- PubMed ID: 10.1007/s10571-021-01052-z, Proteomic Profiling of Cerebrum Mitochondria, Myelin Sheath, and Synaptosome Rev...
- PubMed ID: 33560469, Shen L,Yang A,Chen X,Xiao S,Liu X,Lin J,Zhao Y,Zhang K,Li C,Ke J,Zhang H,Khan NU...
*More publications can be found for each product on its corresponding product page