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- Table of Contents
METTL1 Antibodies
AND METTL1 ELISA kits, METTL1 Proteins
Many biological assays use antibodies to detect METTL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with METTL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop METTL1 antibodies...
Designing an IHC experiment for METTL1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the METTL1 IHC GuideMETTL1 Infographic by Boster Bio
All METTL1 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A15133
100 µg/vial
Cat # A15133
100 µg/vial
Human
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A10023-1
100 µg/vial
Cat # A10023-1
100 µg/vial
Anti-METTL14 Antibody Picoband®
3 Citations
Human
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A07389-2
100 μg/vial
Cat # A07389-2
100 μg/vial
Human
$960
Cat # LS064745
20 µg, 100 µg
Cat # LS064745
20 µg, 100 µg
Human
$628
Cat # LS399818
20 µg, 100 µg
Cat # LS399818
20 µg, 100 µg
Human, Monkey, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M07389-1
100 μl/vial
Cat # M07389-1
100 μl/vial
METTL1 Overview
Facts about tRNA (guanine-N(7)-)-methyltransferase.
tRNA (guanine-N(7)-)-methyltransferase (METTL1)
Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. .
Gene Information
| Human | |
|---|---|
| Gene Name: | METTL1 |
| Uniprot: | Q9UBP6 |
| Entrez: | 4234 |
Family
| Belongs to: |
|---|
| class I-like SAM-binding methyltransferase superfamily |
Alternative Names
C12orf1; D1075-like gene product; EC 2.1.1.33; FLJ95748; methyltransferase like 1; methyltransferase-like 1; Methyltransferase-like protein 1; TRM8; tRNA (guanine-N(7)-)-methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w
Molecular Weight
Mass (kDA):
31.471 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q14.1 |
| Sequence: | 12; NC_000012.12 (57768471..57772105, complement) |
Tissue Specificity
Ubiquitous.
Subcellular Localizations
Nucleus.
Diseases
- Cell Transformation, Neoplastic
- Malignant Neoplasms
- Lung Neoplasms
- Neoplasms
- Malignant Neoplasm Of Lung
Interacting Proteins
- WDR4
Pathways
- Methylation
PTMs
- Phosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/METTL1
bosterbio.com/bosterbio-gene-info-cards/METTL1
References
PMID: 10329009 by Bahr A., et al. Molecular analysis of METTL1, a novel human methyltransferase-like gene with a high degree of phylogenetic conservation.
PMID: 12403464 by Alexandrov A., et al. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.