METTL1 Antibodies

AND METTL1 ELISA kits, METTL1 Proteins

Many biological assays use antibodies to detect METTL1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with METTL1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop METTL1 antibodies...

We validate the specificity of these antibodies to METTL1 by testing them on tissues known to express METTL1 positively and negatively. Browse below to find the METTL1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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METTL1 Infographic by Boster Bio

All METTL1 Products

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Product

Figures

Specificity

Applications

Price

Anti-METTL1 Antibody Picoband®

Western blot analysis of METTL1 using anti-METTL1 antibody (A10859-1)

IHC analysis of METTL1 using anti-METTL1 antibody (A10859-1)

Human, Rat

ELISA, IF, IHC, ICC, WB

$370
Cat # A10859-1
100 μg/vial

Human METTL1 Recombinant Protein

SDS-PAGE

$265
Cat # PROTQ9UBP6
Starting from 10ug

METTL1 (NM_005371) Human Over-expression Lysate

METTL1 Human Over-expression Lysates NM_005371

Human

$628
Cat # LS004234
20 µg, 100 µg

METTL1 Overview

Facts about tRNA (guanine-N(7)-)-methyltransferase.

METTL1 3D structure. Source: alphafold

tRNA (guanine-N(7)-)-methyltransferase (METTL1)

Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. .

Gene Information

Human
Gene Name:	METTL1
Uniprot:	Q9UBP6
Entrez:	4234

Family

Belongs to:

class I-like SAM-binding methyltransferase superfamily

Alternative Names

C12orf1; D1075-like gene product; EC 2.1.1.33; FLJ95748; methyltransferase like 1; methyltransferase-like 1; Methyltransferase-like protein 1; TRM8; tRNA (guanine-N(7)-)-methyltransferase; tRNA(m7G46)-methyltransferase; YDL201w

Molecular Weight

Mass (kDA):
31.471 kDA

Genomic Context


Human

Location:	12q14.1
Sequence:	12; NC_000012.12 (57768471..57772105, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Nucleus.

Diseases

Cell Transformation, Neoplastic
Malignant Neoplasms
Lung Neoplasms
Neoplasms
Malignant Neoplasm Of Lung

Interacting Proteins

WDR4

Pathways

Methylation

PTMs

Phosphorylation

Cleavage

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/METTL1

References

PMID: 10329009 by Bahr A., et al. Molecular analysis of METTL1, a novel human methyltransferase-like gene with a high degree of phylogenetic conservation.

PMID: 12403464 by Alexandrov A., et al. Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA.