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- Table of Contents
Facts about Mixed lineage kinase domain-like protein.
Does not have protein kinase activity. .
| Mouse | |
|---|---|
| Gene Name: | Mlkl |
| Uniprot: | Q9D2Y4 |
| Entrez: | 74568 |

| Belongs to: |
|---|
| protein kinase superfamily |

FLJ34389; mixed lineage kinase domain-like protein; mixed lineage kinase domain-like; MLKL
Mass (kDA):
54.317 kDA

| Mouse | |
|---|---|
| Location: | 8|8 E1 |
| Sequence: | 8; |
Highly expressed in thymus, colon, intestine, liver, spleen and lung. Expressed at much lower level in skeletal muscle, heart and kidney. Not detected in brain.




PMID: 22265413 by Sun L., et al. Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase.
PMID: 23835476 by Wu J., et al. Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis.