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- Table of Contents
NEFH Antibodies
AND NEFH ELISA kits, NEFH Proteins
Many biological assays use antibodies to detect NEFH, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NEFH in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NEFH antibodies...
Designing an IHC experiment for NEFH? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NEFH IHC GuideNEFH Infographic by Boster Bio
All NEFH Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A05307
100 μg/vial
Cat # A05307
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M05307-9
20μL, 40μL, 100μL, 200μL
Cat # M05307-9
20μL, 40μL, 100μL, 200μL
NEFH Overview
Facts about Neurofilament heavy polypeptide.
Neurofilament heavy polypeptide (NEFH)
Neurofilaments usually contain three intermediate filament proteins: L, L, and H which are involved in the maintenance of neuronal caliber. NF-H has an important function in mature axons that isn't subserved by the two smaller NF proteins.
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Gene Information
| Human | |
|---|---|
| Gene Name: | NEFH |
| Uniprot: | P12036 |
| Entrez: | 4744 |
Family
| Belongs to: |
|---|
| intermediate filament family |
Alternative Names
200 kDa neurofilament protein; KIAA0845; NEFH; Neurofilament Heavy (200kDa); neurofilament heavy polypeptide; Neurofilament triplet H protein; neurofilament, heavy polypeptide 200kDa; neurofilament, heavy polypeptide; NF200; NFH; NF-H
Molecular Weight
Mass (kDA):
112.479 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 22q12.2 |
| Sequence: | 22; NC_000022.11 (29480218..29491390) |
Subcellular Localizations
Cytoplasm.
Diseases
- Neoplasms
- Sclerosis
- Primary Lateral Sclerosis
- Amyotrophic Lateral Sclerosis
- Malignant Neoplasms
- Neurofibromatoses
- Neurofibromatosis 2
- Nervousness
- Carcinoma
- Neurilemmoma
- Nerve Degeneration
- Acoustic Neuroma
- Esophageal Neoplasms
Pathways
- Localization
- Methylation
- Pathogenesis
- Cell Proliferation
- Gene Silencing
- Dna Methylation
- Reflex
- Cell Cycle
- Cellular Localization
PTMs
- Phosphorylation
Research Areas
- Cell Biology
- Cellular Markers
- Neurodegeneration
- Neuronal Cell Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NEFH
bosterbio.com/bosterbio-gene-info-cards/NEFH
References
PMID: 3138108 by Lees J.F., et al. The structure and organization of the human heavy neurofilament subunit (NF-H) and the gene encoding it.
PMID: 8621664 by Mukai H., et al. PKN associates and phosphorylates the head-rod domain of neurofilament protein.
21 Publications of Boster NEFH Antibodies & ELISA Kits
- PubMed ID: PMID:31966489, Gene silencing NMII promotes axonal regeneration against contusive spinal cord i...
- PubMed ID: 10.3727/096368910X528102, Bone Marrow Mesenchymal Stem Cells and Electroacupuncture Downregulate the Inhib...
- PubMed ID: 10.3109/09273948.2013.806989, Improved Retinal Ganglion Cell Survival through Retinal Microglia Suppression by...
- PubMed ID: 10.26355/eurrev_201712_14018, Apolipoprotein E 4 triggers multiple pathway-mediated Ca2+ overload, causes CaMK...
- PubMed ID: 10.12659/MSM.900893, Changes in the Expression of miR-34a and its Target Genes Following Spinal Cord ...
- PubMed ID: 10.1186/s12974-016-0546-2, Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type ...
- PubMed ID: 10.1093/jnen/nlv003, Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of P...
- PubMed ID: 10.1038/sc.2008.112, Vaccination with dendritic cells pulsed with homogenate protein of spinal cord p...
- PubMed ID: 10.1021/acsami.1c01904, Biocompatible Chitin Hydrogel Incorporated with PEDOT Nanoparticles for Peripher...
- PubMed ID: 10.1016/j.neulet.2015.04.038, Human mesenchymal stem cells improve the neurodegeneration of femoral nerve in a...
- PubMed ID: 10.1016/j.neulet.2013.10.024, Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon de...
- PubMed ID: 10.1016/j.brainres.2010.08.072, Implantation of adult bone marrow-derived mesenchymal stem cells transfected wit...
- PubMed ID: 10.1007/s12031-013-0114-5, Endogenous Subventricular Zone Neural Progenitors Contribute to the Formation an...
- PubMed ID: 10.1007/s10072-014-2014-z, Altered expression of neurofilament 200 and amyloid-β peptide (1–40) in a rat...
- PubMed ID: , Cograft of neural stem cells and schwann cells overexpressing TrkC and neurotrop...
- PubMed ID: 33285262, Wu K,Yue J,Shen K,He J,Zhu G,Liu S,Zhang C,Yang H. Increased Expression of Fibro...
- PubMed ID: 23979841, Neuron-derived IgG Protects Neurons from Complement-dependent Cytotoxicity
- PubMed ID: 23935920, An Acetylcholinesterase Antibody-Based Quartz Crystal Microbalance for the Rapid...
- PubMed ID: 26238991, Lentiviral-mediated growth-associated protein-43 modification of bone marrow mes...
- PubMed ID: 23371461, Zhang Ym, Zhang Yq, Cheng Sb, Chen Sx, Chen Al, Tang Cz. Chin J Integr Med. 2013...
- PubMed ID: 23334598, He Jj, Li S, Shu Hf, Yu Sx, Liu Sy, Yin Q, Yang H. J Neuropathol Exp Neurol. 201...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page