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- Table of Contents
NOS3 Antibodies
AND NOS3 ELISA kits, NOS3 Proteins
Many biological assays use antibodies to detect NOS3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with NOS3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop NOS3 antibodies...
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NOS3 Infographic by Boster Bio
All NOS3 Products
Product
Figures
Specificity
Applications
Price
Anti-eNOS/NOS3 Antibody Picoband®
32 Citations 16 Q&As
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01604-2
100 μg/vial
Cat # A01604-2
100 μg/vial
Human, Mouse, Rat
ELISA
$480
Cat # EKC1929
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1929
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2316
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2316
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2397
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2397
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2398
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2398
1 kit, containing two 96-well plates and all necessary reagents
Human
ELISA
$499
Cat # EK0754
96 wells/kit, with removable strips.
Cat # EK0754
96 wells/kit, with removable strips.
Anti-eNOS/NOS3 Antibody Picoband®
1 Citations
Human
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A01604-3
100 μg/vial
Cat # A01604-3
100 μg/vial
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01604-2
20μL, 40μL, 100μL, 200μL
Cat # M01604-2
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
IHC, WB
$370
Cat # M01604-3
100 μl/vial
Cat # M01604-3
100 μl/vial
NOS3 Overview
Facts about Nitric oxide synthase, endothelial.
Nitric oxide synthase, endothelial (NOS3)
Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | NOS3 |
| Uniprot: | P29474 |
| Entrez: | 4846 |
Family
| Belongs to: |
|---|
| NOS family |
Alternative Names
Constitutive NOS; EC 1.14.13.39; ECNOS; Endothelial NOS; endothelial; eNOS; eNOScNOS; nitric oxide synthase 3 (endothelial cell); NOS type III; NOS3; NOSIII
Molecular Weight
Mass (kDA):
133.275 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 7q36.1 |
| Sequence: | 7; NC_000007.14 (150991017..151014588) |
Tissue Specificity
Platelets, placenta, liver and kidney.
Subcellular Localizations
Cell membrane. Membrane, caveola. Cytoplasm, cytoskeleton. Golgi apparatus. Specifically associates with actin cytoskeleton in the G2 phase of the cell cycle; which is favored by interaction with NOSIP and results in a reduced enzymatic activity.
Diseases
- Hypertensive Disease
- Diabetes Mellitus
- Atherosclerosis
- Ischemia
- Cardiovascular Diseases
- Inflammation
- Tumor Angiogenesis
- Pathologic Vasoconstriction
- Infarction
- Tissue Adhesions
- Myocardial Infarction
- Hypoxia
Interacting Proteins
- ACTB
- AKT1
- CDC37
- CTNNB1
- DNM1
- GOLGA2
- HBA1
- NOSTRIN
- ST13
Pathways
- Vasodilation
- Pathogenesis
- Angiogenesis
- Localization
- Vasoconstriction
- Cell Proliferation
- Excretion
- Cell Adhesion
- Transport
- Aging
- Secretion
- Platelet Aggregation
- Cell Death
PTMs
- Phosphorylation
- Nitration
- Oxidation
- Reduction
- Dephosphorylation
- Nitrosylation
- Cleavage
- Acetylation
- Methylation
- Myristoylation
Research Areas
- Cancer
- HIF Target Genes
- Hypoxia
- Neuroscience
- Neurotransmission
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/NOS3
bosterbio.com/bosterbio-gene-info-cards/NOS3
References
PMID: 1378832 by Janssens S.P., et al. Cloning and expression of a cDNA encoding human endothelium-derived relaxing factor/nitric oxide synthase.
PMID: 1379542 by Marsden P.A., et al. Molecular cloning and characterization of human endothelial nitric oxide synthase.
24 Publications of Boster NOS3 Antibodies & ELISA Kits
- PubMed ID: PMID:17417610, Inhibition by brimonidine of forskolin-induced nitric oxide synthase expression ...
- PubMed ID: 10.3760/cma.j.issn.0366-6999.2009.24.026, Propofol improves cardiac functional recovery after ischemia-reperfusion by upre...
- PubMed ID: 10.1159/000100961, Research on the Age-Related Changes in the Nitric Oxide Pathway in the Arteries ...
- PubMed ID: 10.1111/j.1755-5922.2009.00071.x, Effects of Quercetin on Gene and Protein Expression of NOX and NOS after Myocard...
- PubMed ID: 10.1039/C6FO00288A, Fucoidan from Undaria pinnatifida prevents vascular dysfunction through PI3K/Akt...
- PubMed ID: 10.1016/j.joms.2008.06.077, Effects of Calcitonin Gene-Related Peptide on the Expression and Activity of Nit...
- PubMed ID: 10.1016/j.ejphar.2009.08.023, Sesamin improves endothelial dysfunction in renovascular hypertensive rats fed w...
- PubMed ID: 10.1016/j.ejphar.2007.09.013, Protective effects of 2,3,5,4′-tetrahydroxystilbene-2-O-beta-d-glucoside, an a...
- PubMed ID: 10.1016/j.ecoenv.2021.112257, Increased secretion of VEGF-C from SiO2-induced pulmonary macrophages promotes l...
- PubMed ID: 10.1007/s12035-015-9347-3, Autologous Bone Marrow Mononuclear Cell Transplantation Delays Progression of Ca...
- PubMed ID: 10.1002/ptr.3691, 2,3,4′,5‐Tetrahydroxystilbene‐2‐O‐β‐d‐glucoside Inhibits Prolifer...
- PubMed ID: 33933809, Zhang J,Cui J,Li X,Hao X,Guo L,Wang H,Liu H.Increased secretion of VEGF-C from S...
- PubMed ID: 33581257, Qu K,Cha H, Ru Y,Que H,Xing M.Buxuhuayu Decoction Accelerates Angiogenesis by Ac...
- PubMed ID: 31309562, Cai P,Lu Z,Jiang T,Wang Z,Yang Y,Zheng L,Zhao J.Syndecan-4 involves in the patho...
- PubMed ID: 25707518, The Puerarin improves renal function in STZ-induced diabetic rats by attenuating...
- PubMed ID: 28710931, Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium
- PubMed ID: 15973775, Expression of endothelial nitric oxide synthase and vascular endothelial growth ...
- PubMed ID: 23426387, Chen Y, Zhang S, Peng G, Yu J, Liu T, Meng R, Li Z, Zhao Y, Wu G. Int J Oncol. 2...
- PubMed ID: 23624755, Zhang Jx, Yang Jr, Chen Gx, Tang Lj, Li Wx, Yang H, Kong X. Acta Pharmacol Sin. ...
- PubMed ID: 25797533, Kong L, Wei Q, Fedail Js, Shi F, Nagaoka K, Watanabe G. J Reprod Dev. 2015;61(3)...
- PubMed ID: 21194187, Zhang W, Wei Qw, Wang Zc, Ding W, Wang W, Shi Fx. J Zhejiang Univ Sci B. 2011 Ja...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page