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- Table of Contents
Nanos homolog 1 Antibodies
AND Nanos1 ELISA kits, Nanos homolog 1 Proteins
Many biological assays use antibodies to detect Nanos homolog 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nanos homolog 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nanos homolog 1 antibodies...
Designing an IHC experiment for Nanos homolog 1? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NANOS1 IHC GuideNanos1 Infographic by Boster Bio
All Nanos1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$540
Cat # EKC2243
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2243
1 kit, containing two 96-well plates and all necessary reagents
Nanos1 Overview
Facts about Nanos homolog 1.
Nanos homolog 1 (Nanos1)
May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that partners with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin.
Up-regulates the creation of MMP14 to promote tumor cell invasion (By similarity). Not essential for normal development.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nanos1 |
| Uniprot: | Q80WY3 |
| Entrez: | 332397 |
Family
| Belongs to: |
|---|
| nanos family |
Alternative Names
nanos homolog 1 (Drosophila); nanos homolog 1; NOS-1; NOS1EC_Rep1a
Molecular Weight
Mass (kDA):
28.151 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 19|19 D3 |
| Sequence: | 19; |
Tissue Specificity
Expressed in the oocyte. Transiently expressed in eight-cell embryos. At 12.5 dpc, it is re-expressed in the central nervous system and the expression continues in the adult brain, in which the hippocampal formation is the predominant region. Expressed in the seminiferous tubules of mature testis, but not in the primordial germ cells.
Diseases
- Cell Invasion
- Congenital Abnormality
- Tissue Adhesions
- Neoplasm Invasiveness
- Malignant Neoplasms
- Neoplasms
- Abnormal Degeneration
- Neoplasm Metastasis
- Disease Of Adrenal Medulla
- Epithelioma
- Lung Neoplasms
- Tumor Progression
- Malignant Neoplasm Of Breast
Pathways
- Cell Development
- Germ Cell Development
- Translation
- Localization
- Cell Migration
- Fertilization
- Cell Differentiation
- Rna Localization
- Cell Cycle
- Oogenesis
- Transport
- Cell Adhesion
- Epithelial Cell-cell Adhesion
PTMs
- Cleavage
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nanos1
bosterbio.com/bosterbio-gene-info-cards/Nanos1
References
PMID: 12834871 by Haraguchi S., et al. nanos1: a mouse nanos gene expressed in the central nervous system is dispensable for normal development.