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- Table of Contents
Nanos homolog 3 Antibodies
AND Nanos3 ELISA kits, Nanos homolog 3 Proteins
Many biological assays use antibodies to detect Nanos homolog 3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Nanos homolog 3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Nanos homolog 3 antibodies...
Designing an IHC experiment for Nanos homolog 3? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the NANOS3 IHC GuideNanos3 Infographic by Boster Bio
All Nanos3 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$540
Cat # EKC2394
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2394
1 kit, containing two 96-well plates and all necessary reagents
Nanos3 Overview
Facts about Nanos homolog 3.
Nanos homolog 3 (Nanos3)
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing an extended transit in G1 phase. Affects cell proliferation probably by repressing translation of certain mRNAs.
Maintains the germ cell lineage by curbing both Bax- dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Nanos3 |
| Uniprot: | P60324 |
| Entrez: | 244551 |
Family
| Belongs to: |
|---|
| nanos family |
Alternative Names
MGC120114; nanos homolog 3 (Drosophila); nanos homolog 3; NOS-3; NOS3NANOS1L
Molecular Weight
Mass (kDA):
19.241 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 8|8 C2 |
| Sequence: | 8; |
Tissue Specificity
Expressed in undifferentiated spermatogonial cells.
Diseases
- Seminoma
- Infertility
- Skin Wound
- Testicular Neoplasms
- Premature Menopause
- Vitamin A Deficiency
- Male Infertility
- Tissue Adhesions
- Sterility
- Neoplasms, Germ Cell And Embryonal
- Ovarian Failure, Premature
- Carcinoma
Pathways
- Cell Development
- Germ Cell Development
- Spermatogenesis
- Cell Cycle
- Cell Death
- Cell Differentiation
- Oogenesis
- Cell Adhesion
- Osteoblast Differentiation
- G2 Phase
- G1 Phase
- Somitogenesis
- Dna Methylation
PTMs
- Demethylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Nanos3
bosterbio.com/bosterbio-gene-info-cards/Nanos3
References
PMID: 12947200 by Tsuda M., et al. Conserved role of nanos proteins in germ cell development.
PMID: 17138666 by Suzuki A., et al. Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development.