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- Table of Contents
Platelet factor 4 Antibodies
AND PF4 ELISA kits, Platelet factor 4 Proteins
Many biological assays use antibodies to detect Platelet factor 4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Platelet factor 4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Platelet factor 4 antibodies...
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PF4 Infographic by Boster Bio
All PF4 Products
Product
Figures
Specificity
Applications
Price
Human CXCL4/PF4 ELISA Kit PicoKine®
8 Citations 11 Q&As
Human
ELISA
$499
Cat # EK0726
96 wells/kit, with removable strips.
Cat # EK0726
96 wells/kit, with removable strips.
Mouse CXCL4/PF4 ELISA Kit PicoKine®
3 Citations 8 Q&As
Mouse
ELISA
$499
Cat # EK0727
96 wells/kit, with removable strips.
Cat # EK0727
96 wells/kit, with removable strips.
Human
IHC, WB, ELISA (Cap)
$370
Cat # PA1446
100 μg/vial
Cat # PA1446
100 μg/vial
Mouse
ELISA
$500
Cat # EZ0727
For 5 plates, 96 wells each
Cat # EZ0727
For 5 plates, 96 wells each
Rat CXCL4/PF4 ELISA Kit PicoKine®
1 Citations 7 Q&As
Rat
ELISA
$499
Cat # EK1651
96 wells/kit, with removable strips.
Cat # EK1651
96 wells/kit, with removable strips.
Rat
ELISA
$500
Cat # EZ1651
For 5 plates, 96 wells each
Cat # EZ1651
For 5 plates, 96 wells each
Mouse
ELISA
$499
Cat # FEK0727
96 wells/kit, with removable strips.
Cat # FEK0727
96 wells/kit, with removable strips.
Human CXCL4/PF4 PicoKine® Quick ELISA Kit
2 Citations
Human
ELISA
$499
Cat # FEK0726
96 wells/kit, with removable strips.
Cat # FEK0726
96 wells/kit, with removable strips.
Human
Cell Culture
$77
Cat # PROTP02776-6
5ug,20ug,100ug
Cat # PROTP02776-6
5ug,20ug,100ug
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M00871-1
100 μg
Cat # M00871-1
100 μg
PF4 Overview
Facts about Platelet factor 4.
Platelet factor 4 (PF4)
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule.
Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the brief form is a stronger inhibitor than the longer form.
Gene Information
| Human | |
|---|---|
| Gene Name: | PF4 |
| Uniprot: | P02776 |
| Entrez: | 5196 |
Family
| Belongs to: |
|---|
| intercrine alpha (chemokine CxC) family |
Alternative Names
chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; CXCL4; CXCL4iroplact; Iroplact; MGC138298; Oncostatin-A; PF4; PF-4; platelet factor 4; SCYB4oncostatin-A
Molecular Weight
Mass (kDA):
10.845 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 4q13.3 |
| Sequence: | 4; NC_000004.12 (73980811..73982124, complement) |
Subcellular Localizations
Secreted.
Diseases
- Heparin-induced Thrombocytopenia
- Thrombosis
- Heparin-induced Thrombocytopenia (hit)
- Hemorrhage
- Blood Coagulation Disorders
- Tissue Adhesions
- Neoplasms
- Inflammation
- Infarction
- Myocardial Infarction
- Thromboembolism
- Malignant Neoplasms
- Atherosclerosis
Interacting Proteins
- APOH
- CCL11
- CCL13
- CCL17
- CCL2
- CCL20
- CCL21
- CCL25
- CCL26
- CCL28
Pathways
- Platelet Activation
- Coagulation
- Platelet Aggregation
- Pathogenesis
- Secretion
- Angiogenesis
- Fibrinolysis
- Immune Response
- Hemostasis
- Cell Proliferation
- Blood Coagulation
- Localization
- Chemotaxis
PTMs
- Cleavage
- Phosphorylation
- Nitration
- Sulphation
- Biotinylation
- Glycosylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PF4
bosterbio.com/bosterbio-gene-info-cards/PF4
References
PMID: 3098319 by Poncz M., et al. Cloning and characterization of platelet factor 4 cDNA derived from a human erythroleukemic cell line.
PMID: 1695112 by Eisman R., et al. Structural and functional comparison of the genes for human platelet factor 4 and PF4alt.
3 Publications of Boster Platelet factor 4 Antibodies & ELISA Kits
- PubMed ID: 10.1080/08916934.2020.1777283, CXCL4 promoted the production of CD4+CD25+FOXP3+treg cells in mouse sepsis model...
- PubMed ID: 10.1016/j.molimm.2020.01.017, Cangrelor alleviates bleomycin-induced pulmonary fibrosis by inhibiting platelet...
- PubMed ID: 10.1016/j.cyto.2019.154878, Platelet-derived alpha-granules are associated with inflammation in patients wit...
*More publications can be found for each product on its corresponding product page