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- Table of Contents
PTH1R Antibodies
AND PTH1R ELISA kits, PTH1R Proteins
Many biological assays use antibodies to detect PTH1R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with PTH1R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop PTH1R antibodies...
Designing a Western blot for PTH1R? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PTH1R Western Blot GuidePTH1R Infographic by Boster Bio
All PTH1R Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
IHC, ICC, WB
$370
Cat # PA2132
100 μg/vial
Cat # PA2132
100 μg/vial
Human, Monkey
ELISA, Flow Cytometry, WB
$370
Cat # A01588
100 μg/vial
Cat # A01588
100 μg/vial
Human
$960
Cat # LS005745
20 µg, 100 µg
Cat # LS005745
20 µg, 100 µg
PTH1R Overview
Facts about Parathyroid hormone/parathyroid hormone-related peptide receptor.
Parathyroid hormone/parathyroid hormone-related peptide receptor (PTH1R)
Receptor for parathyroid hormone and for parathyroid hormone-related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system.
.
Gene Information
| Human | |
|---|---|
| Gene Name: | PTH1R |
| Uniprot: | Q03431 |
| Entrez: | 5745 |
Family
| Belongs to: |
|---|
| G-protein coupled receptor 2 family |
Alternative Names
MGC138426; parathyroid hormone 1 receptorMGC138452; parathyroid hormone/parathyroid hormone-related peptide receptor; parathyroid hormone/parathyroid hormone-related protein receptor; PFE; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; PTH1R; PTHR; PTHR1; PTHRPTHR1parathyroid hormone receptor 1; seven transmembrane helix receptor
Molecular Weight
Mass (kDA):
66.361 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 3p21.31 |
| Sequence: | 3; NC_000003.12 (46877689..46903799) |
Tissue Specificity
Expressed in most tissues. Most abundant in kidney, bone and liver.
Subcellular Localizations
Cell membrane; Multi-pass membrane protein.
Diseases
- Osteoporosis
- Malignant Neoplasms
- Hypercalcemia
- Neoplasms
- Osteosarcoma
- Kidney Failure
- Hypertrophy
- Kidney Diseases
- Bone Diseases
- Kidney Failure, Chronic
- Humoral Hypercalcemia Of Malignancy (disorder)
- Osteopenia
Interacting Proteins
- CTNNB1
- PTH
- PTHLH
Pathways
- Bone Resorption
- Localization
- Cell Proliferation
- Endocytosis
- Osteoblast Differentiation
- Receptor Internalization
- Pathogenesis
- Bone Remodeling
- Secretion
- Transport
- Bone Development
- Ossification
- Ion Homeostasis
PTMs
- Phosphorylation
- Cleavage
- Dephosphorylation
Research Areas
- GPCR
- Neuroscience
- Signal Transduction
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PTH1R
bosterbio.com/bosterbio-gene-info-cards/PTH1R
References
PMID: 8386612 by Schipani E., et al. Identical complementary deoxyribonucleic acids encode a human renal and bone parathyroid hormone (PTH)/PTH-related peptide receptor.
PMID: 8397094 by Schneider H., et al. Cloning and functional expression of a human parathyroid hormone receptor.
3 Publications of Boster PTH1R Antibodies & ELISA Kits
- PubMed ID: 29039525, The association between parathyroid hormone 1?34 and the Wnt/?-catenin signaling...
- PubMed ID: 27069479, Effects of Intermittent Administration of Parathyroid Hormone (1-34) on Bone Dif...
- PubMed ID: 26000041, TGF-? Induces Degradation of PTHrP Through Ubiquitin-Proteasome System in Hepato...
*More publications can be found for each product on its corresponding product page