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- Table of Contents
Paxillin Antibodies
AND PXN ELISA kits, Paxillin Proteins
Many biological assays use antibodies to detect Paxillin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Paxillin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Paxillin antibodies...
Designing a Western blot for Paxillin? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the PXN Western Blot GuidePXN Infographic by Boster Bio
All PXN Products
Product
Figures
Specificity
Applications
Price
Anti-Paxillin/PXN Antibody Picoband®
3 Citations
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PA1804
100 μg/vial
Cat # PA1804
100 μg/vial
Anti-Paxillin/PXN Antibody Picoband®
1 Citations
Human, Mouse, Rat
ELISA, Flow Cytometry, IHC, WB
$370
Cat # A01033-2
100 μg/vial
Cat # A01033-2
100 μg/vial
Human, Mouse, Rat
WB
$370
Cat # P01033
100 μl
Cat # P01033
100 μl
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M01033
100 μl
Cat # M01033
100 μl
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M01033-3
20μL, 40μL, 100μL, 200μL
Cat # M01033-3
20μL, 40μL, 100μL, 200μL
Human, Mouse, Rat
ELISA, IF, IHC, WB
$380
Cat # A01033Y88
100ul
Cat # A01033Y88
100ul
Human, Mouse, Rat
ELISA
$540
Cat # EKC2492
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2492
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$540
Cat # EKC2491
1 kit, containing two 96-well plates and all necessary reagents
Cat # EKC2491
1 kit, containing two 96-well plates and all necessary reagents
Human, Mouse, Rat
ELISA
$480
Cat # EKC1443
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1443
1 kit, containing one 96-well plate and all necessary reagents
PXN Overview
Facts about Paxillin.
Paxillin (PXN)
Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). .
Gene Information
| Human | |
|---|---|
| Gene Name: | PXN |
| Uniprot: | P49023 |
| Entrez: | 5829 |
Family
| Belongs to: |
|---|
| paxillin family |
Alternative Names
FLJ16691; Paxillin; PXN
Molecular Weight
Mass (kDA):
64.505 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 12q24.23 |
| Sequence: | 12; NC_000012.12 (120210439..120265771, complement) |
Subcellular Localizations
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cytoplasm, cell cortex. Colocalizes with integrins at the cell periphery. Colocalize with PXN to membrane ruffles and the leading edge of migrating cells (PubMed:23128389).
Diseases
- Tissue Adhesions
- Malignant Neoplasms
- Neoplasms
- Carcinoma
- Neoplasm Metastasis
- Cell Invasion
- Malignant Neoplasm Of Breast
- Mammary Neoplasms
- Neoplasm Invasiveness
- Cell Transformation, Neoplastic
- Inflammation
- Tumor Angiogenesis
- Malignant Paraganglionic Neoplasm
Interacting Proteins
- CSK
- CTNNB1
- GAB1
- GIT2
- ITGA4
- NDEL1
- PIK3R1
- PTK2
- PTPN11
- RNF5
Pathways
- Cell Adhesion
- Cell Migration
- Localization
- Cell Motility
- Cell Growth
- Cell Proliferation
- Focal Adhesion Assembly
- Cell Cycle
- Secretion
- Angiogenesis
- Cell Death
- Cell Differentiation
- Chemotaxis
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
- Ribosylation
- Geranylgeranylation
- Amidation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/PXN
bosterbio.com/bosterbio-gene-info-cards/PXN
References
PMID: 7534286 by Salgia R., et al. Molecular cloning of human paxillin, a focal adhesion protein phosphorylated by P210BCR/ABL.
PMID: 9054445 by Mazaki Y., et al. Monocyte cells and cancer cells express novel paxillin isoforms with different binding properties to focal adhesion proteins.
3 Publications of Boster Paxillin Antibodies & ELISA Kits
- PubMed ID: 24637093, Zhong S, Luo R, Wang X, Tang L, Wu J, Wang J, Huang R, Sun H, Huang N. Colloids ...
- PubMed ID: 25337216, Liu Y, Zhu Z, Xiong Z, Zheng J, Hu Z, Qiu J. Int J Clin Exp Pathol. 2014 Aug 15;...
- PubMed ID: 24876153, Zhu Z, Liu Y, Li K, Liu J, Wang H, Sun B, Xiong Z, Jiang H, Zheng J, Hu Z. Carci...
*More publications can be found for each product on its corresponding product page