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- Table of Contents
Protein S100-B Antibodies
AND S100B ELISA kits, Protein S100-B Proteins
Many biological assays use antibodies to detect Protein S100-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein S100-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein S100-B antibodies...
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S100B Infographic by Boster Bio
All S100B Products
Product
Figures
Specificity
Applications
Price
Anti-S-100(Beta-subunit) S100b Antibody (Monoclonal, SH-B1)
42 Citations 16 Q&As
Human, Rabbit, Rat
IHC
$370
Cat # MA1088
100 μg/vial
Cat # MA1088
100 μg/vial
Anti-S100 beta/S100B Antibody Picoband®
2 Citations 15 Q&As
Human, Mouse, Rat
WB
$370
Cat # PA1303
100 μg/vial
Cat # PA1303
100 μg/vial
Anti-S100B/S100 Beta Rabbit Monoclonal Antibody
12 Citations 16 Q&As
Human, Mouse, Rat
IP, IF, IHC, ICC, WB
$370
Cat # M00979-1
100 μl
Cat # M00979-1
100 μl
Human
IHC, WB
$449
Cat # M00979-2
100uL
Cat # M00979-2
100uL
Human, Mouse, Rat
ELISA, IP, IF, IHC, WB
$146
Cat # M00979-4
20μL, 40μL, 100μL, 200μL
Cat # M00979-4
20μL, 40μL, 100μL, 200μL
S100B Overview
Facts about Protein S100-B.
Protein S100-B (S100B)
Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for the two ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding websites.
Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Gene Information
| Human | |
|---|---|
| Gene Name: | S100B |
| Uniprot: | P04271 |
| Entrez: | 6285 |
Family
| Belongs to: |
|---|
| S-100 family |
Alternative Names
beta (neural); NEF; S100 beta; S100 calcium binding protein B; S100 calcium-binding protein B; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain, 10protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100; S100B; S100beta
Molecular Weight
Mass (kDA):
10.713 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.3 |
| Sequence: | 21; NC_000021.9 (46598604..46605243, complement) |
Tissue Specificity
Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues.
Subcellular Localizations
Cytoplasm. Nucleus.
Diseases
- Brain Injuries
- Nervousness
- Neoplasms
- Traumatic Brain Injury
- Cerebrovascular Accident
- Alzheimer's Disease
- Inflammation
- Melanoma
- Craniocerebral Trauma
- Ischemia
- Malignant Neoplasms
- Gliosis
- Brain Ischemia
Interacting Proteins
- AGER
- MDM2
- S100A1
- S100A11
- S100A2
- S100A4
- S100A6
- S100P
- SPG21
- TP53
Pathways
- Secretion
- Pathogenesis
- Cell Proliferation
- Cell Death
- Localization
- Inflammatory Response
- Aging
- Neuroprotection
- Regeneration
- Cell Cycle
- Astrocyte Activation
- Cell Growth
- Neurogenesis
PTMs
- Phosphorylation
- Oxidation
- Cleavage
- Acetylation
- Ubiquitination
- Methylation
- Nitrosylation
- Decarboxylation
Research Areas
- Apoptosis
- Cell Biology
- Cellular Markers
- Neuroscience
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/S100B
bosterbio.com/bosterbio-gene-info-cards/S100B
References
PMID: 2394738 by Allore R.J., et al. Cloning and expression of the human S100 beta gene.
PMID: 4031854 by Jensen R., et al. Characterization of human brain S100 protein fraction: amino acid sequence of S100 beta.
40 Publications of Boster Protein S100-B Antibodies & ELISA Kits
- PubMed ID: 30531086, Olfactory ensheathing cells promote nerve regeneration and functional recovery a...
- PubMed ID: 27772714, NECL1 coated PLGA as favorable conduits for repair of injured peripheral nerve
- PubMed ID: 26455874 , Beneficial effects of EGb761 and vitamin E on haloperidol-induced vacuous chewin...
- PubMed ID: 28672960, Baicalin promotes the viability of Schwann cells in vitro by regulating neurotro...
- PubMed ID: 26949634, Expression of S100B during the innate immune of corneal epithelium against fungi...
- PubMed ID: 26870216, A metanephric adenoma of the kidney associated with polycythemia: A case report
- PubMed ID: 26581550, Dendritic cells and macrophages neurally hard-wired in the lymph node
- PubMed ID: 25682129, Up-regulation of P2X7 receptors mediating proliferation of Schwann cells after ...
- PubMed ID: 24325427, Graft of a Tissue-Engineered Neural Scaffold Serves as a Promising Strategy to R...
- PubMed ID: 29178911, Inhibition of HMGB1 reduces rat spinal cord astrocytic swelling and AQP4 express...
- PubMed ID: 27599453, Pro?neurogenic effects of andrographolide on RSC96 Schwann cells in?vitro
- PubMed ID: 26322102, Different methods for inducing adipose-derived stem cells to differentiate into ...
- PubMed ID: 22684116, Establishment of immortalized Schwann cells derived from rat embryo dorsal root ...
- PubMed ID: 28054637, Liu H, Lv P, Zhu Y, Wu H, Zhang K, Xu F, Zheng L, Zhao J. Sci Rep. 2017 Jan 5;7:...
- PubMed ID: 21660959, Yi M, Yang J, Chen X, Li J, Li X, Wang L, Tan Y, Xiong W, Zhou M, Mccarthy Jb, L...
- PubMed ID: 21486673, Bao Hj, Liu Y, Qin Jh, Xu Cs, Hei Nn, Jaber Jr, Chen Qs. Res Vet Sci. 2011 Dec;9...
- PubMed ID: 25415668, Chen Hx, Tang Sp, Gao Ft, Xu Jl, Jiang Xp, Cao J, Fu Gb, Sun K, Liu Sz, Shi W. M...
- PubMed ID: 24569094, Jin X, Chen Z, Liu X, Liang B, Zhang H, Zhang Z. Brain Res. 2014 Apr 16;1558:84-...
- PubMed ID: 21053261, Yang Lm, Liu Xl, Zhu Qt, Zhang Y, Xi Tf, Hu J, He Cf, Jiang L. J Biomed Mater Re...
- PubMed ID: 25646356, Sun D, Li X, Ma M, Liu J, Xu Y, Ye L, Hou H, Wang C, Li X, Jiang Y. Jpn J Clin O...
- PubMed ID: 16773039, Guo Js, Zeng Ys, Li Hb, Huang Wl, Liu Ry, Li Xb, Ding Y, Wu Lz, Cai Dz. Spinal C...
*Showing only the more recent 20. More publications can be found for each product on its corresponding product page