S1PR2 Antibodies

AND S1PR2 ELISA kits, S1PR2 Proteins

Many biological assays use antibodies to detect S1PR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with S1PR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop S1PR2 antibodies...

We validate the specificity of these antibodies to S1PR2 by testing them on tissues known to express S1PR2 positively and negatively. Browse below to find the S1PR2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for S1PR2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the S1PR2 IHC Guide

S1PR2 Infographic by Boster Bio

All S1PR2 Products

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Product

Figures

Specificity

Applications

Price

S1PR2 (NM_004230) Human Over-expression Lysate

Human

$628
Cat # LS009294
20 µg, 100 µg

Anti-S1PR2 Antibody

Human, Mouse, Rat

ELISA, IP, IF, ICC, WB

$370
Cat # A02904-2
100 μl/vial

Anti-S1PR2 Antibody

Western blot analysis of S1PR2 in HeLa cell lysate with S1PR2 antibody at 1 μg/ml

Immunohistochemistry of S1PR2 in mouse brain tissue with S1PR2 antibody at 10 μg/ml

Immunofluorescence of S1PR2 in mouse brain tissue with S1PR2 antibody at 20 μg/ml

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A02904
0.1 mg

S1PR2 Overview

Facts about Sphingosine 1-phosphate receptor 2.

S1PR2 3D structure. Source: alphafold

Sphingosine 1-phosphate receptor 2 (S1PR2)

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P) (PubMed:10617617). S1P is a bioactive lysophospholipid that elicits diverse physiological effects on most types of cells and tissues (PubMed:10617617).

When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis (PubMed:10617617). Receptor for the chemokine-like protein FAM19A5 (PubMed:29453251).

Gene Information

Human
Gene Name:	S1PR2
Uniprot:	O95136
Entrez:	9294

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

AGR16; EDG5; EDG-5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; GPCR13; GPCR18; H218; LPB2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; S1P2; S1PR2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5; sphingosine-1-phosphate receptor 2

Molecular Weight

Mass (kDA):
38.867 kDA

Genomic Context


Human

Location:	19p13.2
Sequence:	19; NC_000019.10 (10221433..10231331, complement)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Inflammation
Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Tumor Angiogenesis
Osteoporosis
Cell Invasion
Neoplasm Invasiveness
Fibrosis
Metastatic Malignant Neoplasm To The Bone
Rheumatoid Arthritis
Anaphylaxis

Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Arthritis
Pulmonary Edema
Cardiovascular Diseases
Albers-schonberg Disease
Crest Syndrome

Interacting Proteins

ITGB4

Pathways

Cell Migration
Localization
Angiogenesis
Regeneration
Bone Remodeling
Cell Activation
Cell Motility
Anaphylaxis
Pathogenesis
Bone Resorption
Secretion
Adherens Junction Assembly
Muscle Cell Differentiation

Cytokine Secretion
Regulation Of Vascular Permeability
Hypersensitivity
Mast Cell Activation
Platelet Aggregation
Inflammatory Response
Positive Chemotaxis

PTMs

Cleavage

Research Areas

GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/S1PR2

References

PMID: 10617617 by An S., et al. Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5.

PMID: 26805784 by Santos-Cortez R.L., et al. Autosomal-recessive hearing impairment due to rare missense variants within S1PR2.