Semaphorin-3A Antibodies

AND SEMA3A ELISA kits, Semaphorin-3A Proteins

Many biological assays use antibodies to detect Semaphorin-3A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-3A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-3A antibodies...

We validate the specificity of these antibodies to Semaphorin-3A by testing them on tissues known to express SEMA3A positively and negatively. Browse below to find the SEMA3A antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SEMA3A Infographic by Boster Bio

All SEMA3A Products

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Applications

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Anti-Semaphorin 3A/SEMA3A Antibody Picoband®

2 Citations 4 Q&As

Anti-Semaphorin 3A Picoband antibody, PB9353, Western blottingAll lanes: Anti Semaphorin 3A (PB9353) at 0

Human

$370
Cat # PB9353
100 μg/vial

Anti-Semaphorin 3A/SEMA3A Antibody Picoband®

Western blot analysis of Semaphorin 3A using anti-Semaphorin 3A antibody (A01761-1)

Human, Mouse, Rat

ELISA, WB

$370
Cat # A01761-1
100 μg/vial

Anti-SEMA3A (P737) Antibody

Western blot (WB) analysis of SEMA3A (P737) pAb at 1:1000 dilution
Lane1:HEK293T whole cell lysate(40ug)
Lane2:A549 whole cell lysate(40ug)
Lane3:PC3 whole cell lysate(40ug)
Lane4:C6 whole cell lysate(40ug)

Immunohistochemistry (IHC) analyzes of SEMA3A (P737) pAb in paraffin-embedded human breast carcinoma tissue at 1:100

Human, Rat

IHC, WB

$405
Cat # A01761
100ul

Anti-Semaphorin-3A SEMA3A Antibody

Immunohistochemistry analysis of SEMA3A antibody in paraffin-embedded human tonsil tissue

Human, Mouse, Rat

ELISA, IF, IHC

$380
Cat # A01761-2
100ul

Semaphorin 3A (SEMA3A) (NM_006080) Human Over-expression Lysate

Human

$960
Cat # LS010371
20 µg, 100 µg

SEMA3A Overview

Facts about Semaphorin-3A.

SEMA3A 3D structure. Source: alphafold

Semaphorin-3A (SEMA3A)

Involved in the development of the olfactory system and in neuronal control of puberty. Induces the collapse and paralysis of neuronal growth cones.

Could serve as a ligand that guides specific growth cones by a motility-inhibiting mechanism. Binds to the complex neuropilin-1/plexin-1.

Gene Information

Human
Gene Name:	SEMA3A
Uniprot:	Q14563
Entrez:	10371

Family

Belongs to:

semaphorin family

Alternative Names

(semaphorin) 3A; coll-1; collapsin 1; Hsema-I; Hsema-III; MGC133243; sema domain, immunoglobulin domain (Ig), short basic domain, secreted; Sema III; SEMA1; Sema3A; SEMAD; SEMAIII; SEMAL; Semaphorin 3A; semaphorin D; Semaphorin III; semaphorin L; semaphorin-3A; SemD

Molecular Weight

Mass (kDA):
88.889 kDA

Genomic Context


Human

Location:	7q21.11
Sequence:	7; NC_000007.14 (83955777..84515189, complement)

Subcellular Localizations

Secreted.

Diseases

Nervousness
Neoplasms
Tissue Adhesions
Malignant Neoplasms
Tumor Angiogenesis
Crest Syndrome
Muscular Fasciculation
Pathologic Neovascularization
Neoplasm Metastasis
Ischemia
Cell Invasion
Spinal Cord Injuries

Pruritus
Neoplasm Invasiveness
Tumor Progression
Mammary Neoplasms
Cardiac Arrhythmia
Dermatitis, Atopic
Dermatitis

Pathways

Axon Guidance
Cell Migration
Innervation
Angiogenesis
Regeneration
Localization
Pathogenesis
Cell Adhesion
Translation
Transport
Cell Death
System Development
Endocytosis

Secretion
Brain Development
Cell Growth
Rna Interference
Nervous System Development
Chemotaxis
Cell Proliferation

PTMs

Phosphorylation
Cleavage

Oxidation
Myristoylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SEMA3A

References

PMID: 8269517 by Kolodkin A.L., et al. The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules.

PMID: 22416012 by Young J., et al. SEMA3A deletion in a family with Kallmann syndrome validates the role of semaphorin 3A in human puberty and olfactory system development.

1 Publications of Boster Semaphorin-3A Antibodies & ELISA Kits

PubMed ID: 24765144, Zhou H, Wu A, Fu W, Lv Z, Zhang Z. Oncol Lett. 2014 May;7(5):1395-1400. Epub 201...

*More publications can be found for each product on its corresponding product page