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- Table of Contents
Protein SON Antibodies
AND SON ELISA kits, Protein SON Proteins
Many biological assays use antibodies to detect Protein SON, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein SON in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein SON antibodies...
Designing a Western blot for Protein SON? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SON Western Blot GuideDesigning an IHC experiment for Protein SON? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SON IHC GuideSON Infographic by Boster Bio
All SON Products
Product
Figures
Specificity
Applications
Price
Anti-Sonic Hedgehog/SHH Antibody Picoband®
8 Citations
Human, Mouse, Rat
IHC, WB
$370
Cat # PA1072-1
100 μg/vial
Cat # PA1072-1
100 μg/vial
Human, Mouse
ELISA, Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A00288-1
100 μg/vial
Cat # A00288-1
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # M00058
100 μl
Cat # M00058
100 μl
Human, Mouse, Rat
ELISA, IF, ICC, WB
$481
Cat # A03381
0.1 mg
Cat # A03381
0.1 mg
Human, Mouse
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M07619
100 μg
Cat # M07619
100 μg
Human
Cell Culture
$77
Cat # PROTQ15465-6
5ug,20ug,100ug
Cat # PROTQ15465-6
5ug,20ug,100ug
SON Overview
Facts about Protein SON.
Protein SON (SON)
RNA-binding protein that serves as a mRNA splicing cofactor by promoting efficient splicing of transcripts that have weak splice sites. Specifically promotes splicing of many cell-cycle and DNA-repair transcripts that have weak splice sites, such as TUBG1, KATNB1, TUBGCP2, AURKB, PCNT, AKT1, RAD23A, and FANCG.
Probably acts by facilitating the interaction between Serine/arginine-rich proteins such as SRSF2 and the RNA polymerase II. Also binds to DNA; binds to the consensus DNA sequence: 5'- GA[GT]AN[CG][AG]CC-3'.
Gene Information
| Human | |
|---|---|
| Gene Name: | SON |
| Uniprot: | P18583 |
| Entrez: | 6651 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
BASS1C21orf50; Bax antagonist selected in saccharomyces 1; DBP5; DBP-5; FLJ33914; KIAA1019SON3; Negative regulatory element-binding protein; NREBPNRE-binding protein; Protein DBP-5; protein SON; SON DNA binding protein; SON DNA-binding protein, KIAA101910FLJ21099
Molecular Weight
Mass (kDA):
263.83 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 21q22.11 |
| Sequence: | 21; NC_000021.9 (33543038..33577514) |
Tissue Specificity
Widely expressed, with the higher expression seen in leukocyte and heart.
Subcellular Localizations
Nucleus speckle. Colocalizes with the pre-mRNA splicing factor SRSF2.
Diseases
- Leukemia, Myelocytic, Acute
- Myeloid Leukemia
- Leukemia
- Cholangiocarcinoma
- T(8;21)(q22;q22)
- Leukemogenesis
- Liver Carcinoma
- Hepatitis
- Genomic Instability
- Hepatitis B
- Tissue Adhesions
Pathways
- Rna Processing
- Cell Proliferation
- Regulation Of Gene Expression
- Localization
- Rna Splicing
- Translation
- Cell Cycle
- Cell Adhesion
- Protein Splicing
- Mitosis
- Metaphase
- Chromosome Segregation
- Cell Cycle Arrest
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SON
bosterbio.com/bosterbio-gene-info-cards/SON
References
PMID: 11707072 by Reymond A., et al. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map.
PMID: 11306577 by Sun C.-T., et al. Transcription repression of human hepatitis B virus genes by negative regulatory element-binding protein/SON.
2 Publications of Boster Protein SON Antibodies & ELISA Kits
- PubMed ID: 33380798, Cao W,Zhang C,Chen R,Wu Q,Xu R,Zhang L,Zhang X. A Novel Cerebroprotein Hydrolysa...
- PubMed ID: 20938369, Dai J, Ai K, Du Y, Chen G. Pancreas. 2011 Mar;40(2):233-6. Doi: 10.1097/Mpa.0B01...
*More publications can be found for each product on its corresponding product page