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- Table of Contents
Slc12a5 Antibodies
AND Slc12a5 ELISA kits, Slc12a5 Proteins
Many biological assays use antibodies to detect Slc12a5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slc12a5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slc12a5 antibodies...
Designing a Western blot for Slc12a5? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the SLC12A5 Western Blot GuideDesigning an IHC experiment for Slc12a5? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the SLC12A5 IHC GuideSlc12a5 Infographic by Boster Bio
All Slc12a5 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # A04638-2
100 µg/vial
Cat # A04638-2
100 µg/vial
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A04629-1
100 μg/vial
Cat # A04629-1
100 μg/vial
Human, Mouse, Rat
ELISA, IHC, WB
$370
Cat # A04643-2
100 µg/vial
Cat # A04643-2
100 µg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A04648-1
100 μg/vial
Cat # A04648-1
100 μg/vial
Human, Mouse, Rat
ELISA, Flow Cytometry, WB
$370
Cat # A04644-2
100 μg/vial
Cat # A04644-2
100 μg/vial
Slc12a5 Overview
Facts about Solute carrier family 12 member 5.
Solute carrier family 12 member 5 (Slc12a5)
Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As important extruder of intracellular chloride, it establishes the adrenal Cl(-) levels required for bile influx after binding of GABA-A and glycine to their receptors, together with subsequent hyperpolarization and neuronal inhibition.
Involved in the regulation of dendritic spine formation and maturation. .
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Slc12a5 |
| Uniprot: | Q91V14 |
| Entrez: | 57138 |
Family
| Belongs to: |
|---|
| SLC12A transporter family |
Alternative Names
Electroneutral potassium-chloride cotransporter 2; hKCC2; KCC2; KCC2K-Cl cotransporter 2; KIAA1176erythroid K-Cl cotransporter 2; Neuronal K-Cl cotransporter; SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; solute carrier family 12 member 5
Molecular Weight
Mass (kDA):
126.271 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 2|2 H3 |
| Sequence: | 2; |
Tissue Specificity
Isoform 2 expressed in brainstem and spinal cord, isoform 1 expressed in brainstem, spinal cord and olfactory bulb of E17 embryos. Isoforms 1 and 2 expressed in all parts of the brain and spinal cord in postnatal day 14 mice.
Diseases
- Nervousness
- Neuroblastoma
- Schizophrenia
- Depressive Disorder
- Spinal Cord Injuries
- Mood Disorders
- Diabetic Nephropathy
- Gitelman Syndrome
- Hepatitis C, Chronic
- Columnar Cell Change Of The Breast
- Teratocarcinoma
- Lung Diseases
- Carcinogenesis
Pathways
- Transport
- Brain Development
- Cell Motility
- Ion Transport
- Localization
- Reflex
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc12a5
bosterbio.com/bosterbio-gene-info-cards/Slc12a5
References
PMID: 11471062 by Ehringer M.A., et al. High-throughput sequence identification of gene coding variants within alcohol-related QTLs.
PMID: 10077537 by Haapa S., et al. An efficient DNA sequencing strategy based on bacteriophage Mu in vitro DNA transposition reaction.