TMC8 Antibodies

AND TMC8 ELISA kits, TMC8 Proteins

Many biological assays use antibodies to detect TMC8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TMC8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TMC8 antibodies...

We validate the specificity of these antibodies to TMC8 by testing them on tissues known to express TMC8 positively and negatively. Browse below to find the TMC8 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Designing an IHC experiment for TMC8? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.

Open the TMC8 IHC Guide

TMC8 Infographic by Boster Bio

All TMC8 Products

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Specificity

Applications

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Anti-EVER2 TMC8 Antibody

Western blot analysis of EVER2 in Jurkat cell lysate with EVER2 antibody at (A) 1 and (B) 2 μg/mL

Immunohistochemistry of EVER2 in human brain with EVER2 antibody at 5 μg/mL

Immunofluorescence of EVER2 in Human Brain cells with EVER2 antibody at 20 μg/mL

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$481
Cat # A06892-1
0.1 mg

Anti-TMC8/Ever2 Antibody

Western Blot analysis of HeLa cells using TMC8 Polyclonal Antibody

Immunohistochemistry analysis of paraffin-embedded human tonsil, using TMC8 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, WB

$399
Cat # A06892
100μl

TMC8 Overview

Facts about Transmembrane channel-like protein 8.

TMC8 3D structure. Source: alphafold

Transmembrane channel-like protein 8 (TMC8)

Probable ion channel. .

Gene Information

Human
Gene Name:	TMC8
Uniprot:	Q8IU68
Entrez:	147138

Family

Belongs to:

TMC family

Alternative Names

epidermodysplasia verruciformis 2; Epidermodysplasia verruciformis protein 2; EV2; EVER2MGC102701; EVIN2FLJ43684; FLJ40668; MGC40121; transmembrane channel-like 8; transmembrane channel-like protein 8

Molecular Weight

Mass (kDA):
81.641 kDA

Genomic Context


Human

Location:	17q25.3
Sequence:	17; NC_000017.11 (78129298..78142968)

Tissue Specificity

Expressed in placenta, prostate and testis.

Subcellular Localizations

Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Epidermodysplasia Verruciformis
Carcinoma
Skin Diseases, Genetic
Malignant Neoplasms
Papillomavirus Infections
Skin Carcinoma
Skin Neoplasms
Malignant Neoplasm Of Skin
Infective Disorder
Human Papilloma Virus Infection
Papilloma
Uterine Cervical Neoplasm

Malignant Tumor Of Cervix
Immunologic Deficiency Syndromes
Malignant Squamous Cell Neoplasm
Complete Hearing Loss
Common Wart
Malignant Paraganglionic Neoplasm
Basal Cell Carcinoma

Pathways

Pathogenesis
Translation
Oncogenesis

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TMC8

References

PMID: 12426567 by Ramoz N., et al. Mutations in two adjacent novel genes are associated with epidermodysplasia verruciformis.

PMID: 12906855 by Kurima K., et al. Characterization of the transmembrane channel-like (TMC) gene family: functional clues from hearing loss and epidermodysplasia verruciformis.