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- Table of Contents
Tnfrsf12a Antibodies
AND Tnfrsf12a ELISA kits, Tnfrsf12a Proteins
Many biological assays use antibodies to detect Tnfrsf12a, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Tnfrsf12a in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Tnfrsf12a antibodies...
Designing an IHC experiment for Tnfrsf12a? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TNFRSF12A IHC GuideTnfrsf12a Infographic by Boster Bio
All Tnfrsf12a Products
Product
Figures
Specificity
Applications
Price
Human TNFRSF12A/TWEAKR ELISA Kit PicoKine®
1 Citations
Human
ELISA
$499
Cat # EK1753
96 wells/kit, with removable strips.
Cat # EK1753
96 wells/kit, with removable strips.
Anti-TWEAKR Rabbit Monoclonal Antibody
3 Citations
Human, Mouse, Rat
IP, IHC, WB
$370
Cat # M06261
100 μl
Cat # M06261
100 μl
Mouse
ELISA
$499
Cat # EK1754
96 wells/kit, with removable strips.
Cat # EK1754
96 wells/kit, with removable strips.
Human
ELISA, Flow Cytometry, Functional Assay, Kinetics
$486
Cat # M06261-3
100 μg
Cat # M06261-3
100 μg
Mouse
Cell Culture
$77
Cat # PROTO54907
5ug,20ug,100ug
Cat # PROTO54907
5ug,20ug,100ug
Tnfrsf12a Overview
Facts about Tumor necrosis factor receptor superfamily member 12A.
Tumor necrosis factor receptor superfamily member 12A (Tnfrsf12a)
Receptor for TNFSF12/TWEAK (By similarity). Weak inducer of apoptosis in some cell types.
Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Tnfrsf12a |
| Uniprot: | Q9CR75 |
| Entrez: | 27279 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
CD266 antigen; CD266; FGF-inducible 14; Fibroblast growth factor-inducible immediate-early response protein 14; Fn14; FN14tumor necrosis factor receptor superfamily member 12A; TNFRSF12; TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; TWEAK R; TWEAKR; tweak-receptor; type I transmembrane protein Fn14
Molecular Weight
Mass (kDA):
13.641 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 17|17 A3.3 |
| Sequence: | 17; |
Tissue Specificity
Highly expressed in fetal heart, intestine, kidney, liver, lung and skin, and in adult heart and ovary. Intermediate expression in adult kidney, lung and skin.
Diseases
- Inflammation
- Malignant Neoplasms
- Neoplasms
- Neoplasm Metastasis
- Tumor Angiogenesis
- Neoplasm Invasiveness
- Carcinoma
- Reperfusion Injury
- Arthropathy
- Cell Invasion
- Tissue Adhesions
Pathways
- Cell Death
- Angiogenesis
- Transport
- Cell Proliferation
- Aging
- Regeneration
- Cell Adhesion
- Osteoclast Differentiation
- Cell Migration
- Lung Development
- Transcytosis
- Muscle Atrophy
- Inflammatory Response
PTMs
- Phosphorylation
Research Areas
- Angiogenesis
- Apoptosis
- Cancer
- Tumor Suppressors
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Tnfrsf12a
bosterbio.com/bosterbio-gene-info-cards/Tnfrsf12a
References
PMID: 10551889 by Meighan-Mantha R.L., et al. The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration.