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- Table of Contents
Designing a Western blot for Tubulin beta-3 chain? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TUBB3 Western Blot GuideDesigning an IHC experiment for Tubulin beta-3 chain? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TUBB3 IHC Guide
Facts about Tubulin beta-3 chain.
TUBB3 plays a crucial role in proper axon guidance and mantainance. .
| Human | |
|---|---|
| Gene Name: | TUBB3 |
| Uniprot: | Q13509 |
| Entrez: | 10381 |

| Belongs to: |
|---|
| tubulin family |

Beta3-tubulin; beta-4; betaIII Tubulin; beta-III Tubulin; beta-Tubulin III; Class III beta-tubulin; TUBB3; TUBB4 CFEOM3A; Tubulin Beta 3; tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-4; Tubulin beta-III; tubulin, beta 3; TUJ1 antigen; TUJ-1 antigen
Mass (kDA):
50.433 kDA

| Human | |
|---|---|
| Location: | 16q24.3 |
| Sequence: | 16; NC_000016.10 (89921925..89936097) |
Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.
Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, filopodium.





PMID: 9473684 by Ranganathan S., et al. Cloning and sequencing of human betaIII-tubulin cDNA: induction of betaIII isotype in human prostate carcinoma cells by acute exposure to antimicrotubule agents.
PMID: 14736079 by Katsetos C.D., et al. Class III beta-tubulin isotype: a key cytoskeletal protein at the crossroads of developmental neurobiology and tumor neuropathology.
*More publications can be found for each product on its corresponding product page