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- Table of Contents
TJP2 Antibodies
AND TJP2 ELISA kits, TJP2 Proteins
Many biological assays use antibodies to detect TJP2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with TJP2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop TJP2 antibodies...
Designing a Western blot for TJP2? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the TJP2 Western Blot GuideDesigning an IHC experiment for TJP2? The guide has the expected staining pattern, antigen retrieval and fixation, antibodies backed by real IHC images, the tissue controls to run alongside, and protocols taken from published papers.
Open the TJP2 IHC GuideTJP2 Infographic by Boster Bio
All TJP2 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PA1957
100 μg/vial
Cat # PA1957
100 μg/vial
Human, Mouse, Rat
IF, IHC, ICC, WB
$370
Cat # PA1971
100 μg/vial
Cat # PA1971
100 μg/vial
Human, Monkey, Mouse, Rat
Flow Cytometry, IF, IHC, ICC, WB
$370
Cat # A02774-1
100 μg/vial
Cat # A02774-1
100 μg/vial
TJP2 Overview
Facts about Tight junction protein ZO-2.
Tight junction protein ZO-2 (TJP2)
Plays a part in tight junctions and adherens junctions. .
Gene Information
| Human | |
|---|---|
| Gene Name: | TJP2 |
| Uniprot: | Q9UDY2 |
| Entrez: | 9414 |
Family
| Belongs to: |
|---|
| MAGUK family |
Alternative Names
C9DUPq21.11; DFNA51; DUP9q21.11; MGC26306; tight junction protein 2 (zona occludens 2); Tight junction protein 2; TJP2; X104; X104tight junction protein ZO-2; ZO2; ZO-2; ZO2Friedreich ataxia region gene X104 (tight junction protein ZO-2); Zona occludens protein 2; Zonula occludens protein 2
Molecular Weight
Mass (kDA):
133.958 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q21.11 |
| Sequence: | 9; NC_000009.12 (69121006..69255208) |
Tissue Specificity
This protein is found in epithelial cell junctions. Isoform A1 is abundant in the heart and brain. Detected in brain and skeletal muscle. It is present almost exclusively in normal tissues. Isoform C1 is expressed at high level in the kidney, pancreas, heart and placenta. Not detected in brain and skeletal muscle. Found in normal as well as in most neoplastic tissues.
Subcellular Localizations
Cell junction, adherens junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, tight junction. Nucleus. Also nuclear under environmental stress conditions and in migratory endothelial cells and subconfluent epithelial cell cultures.
Diseases
- Neoplasms
- Tissue Adhesions
- Malignant Neoplasms
- Inflammation
- Carcinoma
- Nervousness
- Edema
- Adenocarcinoma
- Cardiovascular Diseases
- Inflammatory Bowel Diseases
- Brain Edema
- Pancreatic Neoplasm
- Hiv Infections
Interacting Proteins
- LASP1
Pathways
- Localization
- Pathogenesis
- Cell Proliferation
- Transport
- Methylation
- Blastocyst Formation
- Cell-cell Adhesion
- Mitosis
- Cell Differentiation
- Establishment Of Cell Polarity
- Inflammatory Response
- Cell Cycle
- Ion Transport
PTMs
- Phosphorylation
- Dephosphorylation
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TJP2
bosterbio.com/bosterbio-gene-info-cards/TJP2
References
PMID: 7951235 by Duclos F., et al. The Friedreich ataxia region: characterization of two novel genes and reduction of the critical region to 300 kb.
PMID: 11018256 by Chlenski A., et al. Organization and expression of the human zo-2 gene (tjp-2) in normal and neoplastic tissues.