Tumor necrosis factor ligand superfamily member 11 (TNFSF11)

Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK.

Osteoclast differentiation and activation element.

Augments the capacity of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and might play a role in the regulation of this T-cell-dependent immune response.