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- Table of Contents
Y-box-binding protein 1 Antibodies
AND YBX1 ELISA kits, Y-box-binding protein 1 Proteins
Many biological assays use antibodies to detect Y-box-binding protein 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Y-box-binding protein 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Y-box-binding protein 1 antibodies...
Designing a Western blot for Y-box-binding protein 1? The guide has the expected band size, antibodies backed by real blot images, the controls to run alongside, and protocols taken from published papers.
Open the YBX1 Western Blot GuideYBX1 Infographic by Boster Bio
All YBX1 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
Flow Cytometry, IF, IHC, IHC-F, ICC, WB
$370
Cat # PB9465
100 μg/vial
Cat # PB9465
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IHC, WB
$370
Cat # PA1758
100 μg/vial
Cat # PA1758
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IP, IF, IHC, ICC, WB
$370
Cat # M01054
100 μl
Cat # M01054
100 μl
YBX1 Overview
Facts about Y-box-binding protein 1.
Y-box-binding protein 1 (YBX1)
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and modulates splice site selection.
Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes.
Gene Information
| Human | |
|---|---|
| Gene Name: | YBX1 |
| Uniprot: | P67809 |
| Entrez: | 4904 |
Family
| Belongs to: |
|---|
| YBX1 family |
Alternative Names
BP-8; CBF-A; class II, Y box-binding protein I; CSDA2; CSDB; DBPB CCAAT-binding transcription factor I subunit A; EFI-A; Enhancer factor I subunit A; MDR-NF1; MGC104858; MGC110976; MGC117250; NSEP1 Y-box-binding protein 1; nuclease-sensitive element-binding protein 1; Y box binding protein 1; YB1 DNA-binding protein B; YB-1 Y-box transcription factor; YBX1
Molecular Weight
Mass (kDA):
35.924 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 1p34.2 |
| Sequence: | 1; NC_000001.11 (42682418..42703805) |
Subcellular Localizations
Cytoplasm. Nucleus. Cytoplasmic granule. Secreted. Secreted, extracellular exosome. Predominantly cytoplasmic in proliferating cells (PubMed:12604611). Cytotoxic stress and DNA damage enhance translocation to the nucleus (PubMed:14718551). Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:25229427). Shuttles between nucleus and cytoplasm (PubMed:25229427). Localized with DDX1, MBNL1 and TIAL1 in stress granules upon stress (PubMed:18335541). Secreted by mesangial and monocytic cells after inflammatory challenges (PubMed:19483673).
Diseases
- Neoplasms
- Malignant Neoplasms
- Mammary Neoplasms
- Neurofibromatosis 1
- Malignant Neoplasm Of Breast
- Carcinoma
- Malignant Paraganglionic Neoplasm
- Cell Transformation, Neoplastic
- Liver Carcinoma
- Neoplasm Metastasis
- Cell Invasion
- Leukemia
- Genotoxic Stress
Interacting Proteins
- C1QBP
- DHX9
- EP300
- FBXO33
- LSM3
- PITX2
- PPM1G
- TPT1
Pathways
- Dna Replication
- Translation
- Localization
- Drug Resistance
- Cell Proliferation
- Methylation
- Dna Repair
- Cell Cycle
- Cell Growth
- Pathogenesis
- Regulation Of Gene Expression
- Transport
- Rna Interference
PTMs
- Phosphorylation
- Methylation
- Cleavage
- Acetylation
- Reduction
Research Areas
- Breast Cancer
- Cancer
- DNA Repair
- Epigenetics
- Ovarian Carcinoma Cell Markers
- Stem Cell Markers
- Transcription Factors and Regulators
- Translation Control
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/YBX1
bosterbio.com/bosterbio-gene-info-cards/YBX1
References
PMID: 2977358 by Sakura H., et al. Two human genes isolated by a novel method encode DNA-binding proteins containing a common region of homology.
PMID: 3174636 by Didier D.K., et al. Characterization of the cDNA encoding a protein binding to the major histocompatibility complex class II Y box.