Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4)

alpha-Smooth Muscle Actin antibody

Boster Bio Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4) catalog # MA1106. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. Cited in 240 publication(s).

Product Info Summary

SKU: MA1106
Size: 100μg/vial
Reactive Species: Human, Mouse, Rat
Host: Mouse
Application: IHC, WB

Product Name

Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4)

View all alpha-Smooth Muscle Actin Antibodies

SKU/Catalog Number







Boster Bio Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4) catalog # MA1106. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4) (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1106)




Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.



Clone Number



Mouse IgG2a


N-terminal synthetic decapeptide of alpha-smooth muscle actin.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross Reactivity

No cross reactivity with other proteins

Reactive Species

MA1106 is reactive to ACTA2 in Human, Mouse, Rat


MA1106 is guaranteed for IHC, WB Boster Guarantee

Background of alpha-Smooth Muscle Actin

Ueyama et al. (1990) assigned the ACTSA gene to chromosome 10 by Southern blot analysis of DNAs from 18 rodent-human somatic cell hybrids. Regional mapping by in situ hybridization localized the gene to 10q22-q24.Assignment of the vascular smooth muscle actin gene ACTSA to human chromosome. Smooth muscle alpha-actin gene requires two E-boxes for proper expression in vivo and is a target of class I basic helix-loop-helix proteins.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence and ELISA with known positive and negative samples to ensure specificity and high affinity.

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Innovating Scientists Reward

If you are the first to review this product, or if you have results for a special sample, species or application this product is not validated in, share your results with us and receive product credits you can use towards any Boster products! Applicable to all scientists world wide.

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Add 1ml of PBS buffer will yield a concentration of 100ug/ml.

Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. Actual working concentration varies and should be decided by the user.

Immunohistochemistry (Paraffin-embedded Section), 0.1-0.5μg/ml, Human, mouse, rat, By Heat
Immunohistochemistry (Frozen Section), 0.1-0.5μg/ml, Human, mouse, rat, -
Western blot, 2μg/ml, Human, mouse, rat

Validation Images & Assay Conditions

Gene/Protein Information For ACTA2 (Source: Uniprot.Org, NCBI)

Uniprot ID


Gene ID


Gene Name


Full Name

Actin, aortic smooth muscle




actin family

Alternative Names

1a4 sma; 1a4 smooth muscle actin; AAT6; ACTA2; Actin alpha 2; actin, alpha 2, smooth muscle, aorta; actin, aortic smooth muscle; ACTSA; ACTVS; alpha 2 actin; alpha sma 1a4; alpha SMA; alpha smooth muscle actin; alpha-actin-2; alpha-SMA; alphaSmooth Muscle Actin; alpha-Smooth Muscle Actin; a-sma; Cell growth-inhibiting gene 46 protein; growth-inhibiting gene 46; MYMY5; sma 1a4; SMA; smooth muscle actin Acta2|actin alpha 2, smooth muscle|actin, aortic smooth muscle|actin, alpha 2, smooth muscle, aorta|alpha-actin-2|smooth muscle alpha-actin

*if product is indicated to react with multiple species, protein info is based on the gene entry specified above in "species".

For more info on ACTA2, check out the ACTA2 Infographic

ACTA2 infographic

We have 30,000+ of these available, one for each gene! check them out.

In this infographic you will see the following information for ACTA2: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact us [email protected]

MA1106 has been cited in 240 publications:

*The publications in this section are manually curated by our staff scientists. They may differ from Bioz's machine gathered results. Both are accurate. If you find a publication citing this product but is missing from this list, please let us know we will issue you a thank-you coupon.

EPHB4 Regulates Human Trophoblast Cell Line HTR-8/SVneo Function: Implications for the Role of EPHB4 in Preeclampsia

Fang L,Wang KK,Zhang PF,Li T,Xiao ZL,Yang M,Yu ZX.Nucleolin promotes Ang II-induced phenotypic transformation of vascular smooth muscle cells by regulating EGF and PDGF-BB.J Cell Mol Med.2020 Jan;24(2) :1917-1933.doi:10.1111/jcmm.14888.Epub 2020 Jan 1.PMI
Species: Rat
MA1106 usage in article: APP:WB, SAMPLE:VSMCS, DILUTION:NA

Shen J,Wei W,Wang X,Yang J,Lu L,Lv X,Xue X.Proliferation of Vascular Smooth Muscle Cells under ox-LDL Is Regulated by Alismatis rhizoma Decoction via InhibitingERK1/2 and miR-17∼92a Cluster Activation.Evid Based Complement Alternat Med.2020 Aug 22;2020:72
Species: Rat
MA1106 usage in article: APP:IHC, SAMPLE:VSMCS, DILUTION:1:1000

Xu T,Pan L,Li L,Hu S,Zhou H,Yang C,Yang J,Li H,Liu Y,Meng X,Li J.MicroRNA-708 modulates Hepatic Stellate Cells activation and enhances extracellular matrix accumulation via direct targeting TMEM88. J Cell Mol Med. 2020 Jul;24(13):7127-7140.doi: 10.1111/jc
Species: Human
MA1106 usage in article: APP:WB, SAMPLE:LX-2 CELLS, DILUTION:1:1000

Liao J, Wu Q, Qian C, Zhao N, Zhao Z, Lu K, Zhang S, Dong Q, Chen L, Li Q, Du Y. TRPV4 blockade suppresses atrial fibrillation in sterile pericarditis rats. JCI Insight. 2020 Oct 29:137528. doi: 10.1172/jci.insight.137528. Epub ahead of print. PMID: 33119
Species: Rat
MA1106 usage in article: APP:IHC, SAMPLA:ATRIA TISSUE, DILUTION:1:50

Yang J, Li J, Tan R, He X, Lin X, Zhong X, Fan J, Wang L. Protocatechualdehyde attenuates obstructive nephropathy through inhibiting lncRNA9884 induced inflammation. Phytother Res. 2020 Oct 28. doi:10.1002/ptr.6 919. Epub ahead of print. PMID: 33118280.
Species: Mouse

Decreased endogenous hydrogen sulfide generation in penile tissues of diabetic rats with erectile dysfunction

Phenotypic switching of vascular smooth muscle cells in animal model of rat thoracic aortic aneurysm

Suppressive effects of 17%u03B2-estradiol on hepatic fibrosis in CCl4-induced rat model

Activation of AMPK by simvastatin inhibited breast tumor angiogenesis via impeding HIF%u20101%u03B1%u2010induced pro%u2010angiogenic factor

Suppression of hypoxia-induced excessive angiogenesis by metformin via elevating tumor blood perfusion

Pioglitazone, a peroxisome proliferator-activated receptor %u03B3 agonist, ameliorates chronic kidney disease by enhancing antioxidative capacity and attenuating %u2026

EPHB4 regulates human trophoblast cell line HTR-8/SVneo function: implications for the role of EPHB4 in preeclampsia

The coordinated roles of miR-26a and miR-30c in regulating TGF?1-induced epithelial-to-mesenchymal transition in diabetic nephropathy

Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-?1

Inhibitory effects of oxymatrine on TGF-?1-induced proliferation and abnormal differentiation in rat cardiac fibroblasts via the p38MAPK and ERK1/2 signaling pathways

Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-?1/Smad pathway

Hydroxysafflor Yellow A Ameliorates Renal Fibrosis by Suppressing TGF-?1-Induced Epithelial-to-Mesenchymal Transition

Autophagic degradation of caveolin-1 promotes liver sinusoidal endothelial cells defenestration

Specific Inhibitor of Smad3 (SIS3) Attenuates Fibrosis, Apoptosis, and Inflammation in Unilateral Ureteral Obstruction Kidneys by Inhibition of Transforming Growth Factor ? (TGF-?)/Smad3 Signaling

miR-185 Inhibits Fibrogenic Activation of Hepatic Stellate Cells and Prevents Liver Fibrosis

Interleukin-10 promotes primary rat hepatic stellate cell senescence by upregulating the expression levels of p53 and p21

Extracorporeal shock wave therapy with low-energy flux density inhibits hypertrophic scar formation in an animal model

The Role and Mechanism of ?-Klotho in the Calcification of Rat Aortic Vascular Smooth Muscle Cells

FOXA2 alleviates CCl4-induced liver fibrosis by protecting hepatocytes in mice

Poly(ethylene glycol)-modified silk fibroin membrane as a carrier for limbal epithelial stem cell transplantation in a rabbit LSCD model

Impact of chronic methamphetamine treatment on the atherosclerosis formation in ApoE?/? mice fed a high cholesterol diet

The rhythmic expression of clock genes attenuated in human plaque-derived vascular smooth muscle cells

Rutin suppresses high glucose-induced ACTA2 and p38 protein expression in diabetic nephropathy

BMP-7 suppresses excessive scar formation by activating the BMP-7/Smad1/5/8 signaling pathway

Long-term intravenous administration of carboxylated single-walled carbon nanotubes induces persistent accumulation in the lungs and pulmonary fibrosis via the nuclear factor-kappa B pathway.

Obtaining spontaneously beating cardiomyocyte-like cells from adipose-derived stromal vascular fractions cultured on enzyme-crosslinked gelatin hydrogels

Evaluation of pharmacological relaxation effect of the natural product naringin on in vitro cultured airway smooth muscle cells and in vivo ovalbumin-induced asthma Balb/c mice

Treatment of diabetes mellitus-induced erectile dysfunction using endothelial progenitor cells genetically modified with human telomerase reverse transcriptase

Hepatic SATB1 induces paracrine activation of hepatic stellate cells and is upregulated by HBx

Mouse Sirt3 promotes autophagy in AngII-induced myocardial hypertrophy through the deacetylation of FoxO1

Inhibitory effects of dimethyl ?-ketoglutarate in hepatic stellate cell activation

IL-9 Inhibits Viral Replication in Coxsackievirus B3-Induced Myocarditis

The protective role of vitamin D3 in a murine model of asthma via the suppression of TGF-?/Smad signaling and activation of the Nrf2/HO-1 pathway

Functional and Proteomic Investigations Reveal Major Royal Jelly Protein 1 Associated with Anti-hypertension Activity in Mouse Vascular Smooth MuscleCells

Signal Transducer and Activator of Transcription 3/MicroRNA-21 Feedback Loop Contributes to Atrial Fibrillation by Promoting Atrial Fibrosis in a Rat Sterile Pericarditis Model

Imperatorin derivative OW1 inhibits the upregulation of TGF-? and MMP-2 in renovascular hypertension-induced cardiac remodeling

Dietary Flavonoid Hyperoside Induces Apoptosis of Activated Human LX-2 Hepatic Stellate Cell by Suppressing Canonical NF-?B Signaling

Macrophage migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and AMPK pathways

The Endothelial Prolyl-4-Hydroxylase Domain 2/Hypoxia-Inducible Factor 2 Axis Regulates Pulmonary Artery Pressure in Mice

Blockade of Orai1 Store-Operated Calcium Entry Protects against Renal Fibrosis

Effect of Huai Qi Huang on Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells through miR-200a

Digoxin reduces atherosclerosis in apolipoprotein E-deficient mice

Polarization-sensitive optical projection tomography for muscle fiber imaging

Wnt/?-catenin pathway is required for epithelial to mesenchymal transition in CXCL12 over expressed breast cancer cells

Identification of cardiac-related circulating microRNA profile in human chronic heart failure

Effect of P2X4R on airway inflammation and airway remodeling in allergic airway challenge in mice

Mesenchymal stem cell-laden anti-inflammatory hydrogel enhances diabetic wound healing.

RAC1 overexpression promotes the proliferation, migration and epithelial-mesenchymal transition of lens epithelial cells

Plumbagin Ameliorates CCl4-Induced Hepatic Fibrosis in Rats via the Epidermal Growth Factor Receptor Signaling Pathway

Involvement of epithelial-to-mesenchymal transition and associated transforming growth factor-?/Smad signaling in paraquat-induced pulmonary fibrosis

Modulation of fatty acid metabolism is involved in the alleviation of isoproterenol-induced rat heart failure by fenofibrate.

Glycyrrhizic acid alleviates bleomycin-induced pulmonary fibrosis in rats

Tissue Transglutaminase-Regulated Transformed Growth Factor-?1 in the Parasite Links Schistosoma japonicum Infection with Liver Fibrosis

An HNF1?-regulated feedback circuit modulates hepatic fibrogenesis via the crosstalk between hepatocytes and hepatic stellate cells

Overexpression of monocarboxylate anion transporter 1 and 4 in T24-induced cancer-associated fibroblasts regulates the progression of bladder cancer cells in a 3D microfluidic device

Dynamic Contrast-Enhanced Magnetic Resonance Imaging with Gd-EOB-DTPA for the Evaluation of Liver Fibrosis Induced by Carbon Tetrachloride in Rats

Mig-6Gene Knockout Induces Neointimal Hyperplasia in the Vascular Smooth Muscle Cell

Rho-Associated Protein Kinases Play an Important Role in the Differentiation of Rat Adipose-Derived Stromal Cells into Cardiomyocytes In Vitro

Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma

Lentivirus vector-mediated Rho guanine nucleotide dissociation inhibitor 2 overexpression induces beta-2 adrenergic receptor desensitization in airway smooth muscle cells

Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats

Thymic Stromal Lymphopoietin Attenuates the Development of Atherosclerosis in ApoE?/? Mice

Suppression of CB1 Cannabinoid Receptor by Lentivirus Mediated Small Interfering RNA Ameliorates Hepatic Fibrosis in Rats

Effects of PPARg agonist pioglitazone on rat hepatic fibrosis

Delta-like 1 Serves as a New Target and Contributor to Liver Fibrosis Down-regulated by Mesenchymal Stem Cell Transplantation

Anti-heat shock protein 70 autoantibody epitope changes and BD091 promotes atherosclerosis in rats

Haemin-enhanced expression of haem oxygenase-1 stabilizes erythrocyte-induced vulnerable atherosclerotic plaques

Regulation of smooth muscle contractility by the epithelium in rat vas deferens: role of ATP-induced release of PGE2

RNA interference targeting the platelet-derived growth factor receptor ? subunit ameliorates experimental hepatic fibrosis in rats

Simultaneous expression of Oct4 and genes of three germ layers in single cell-derived multipotent adult progenitor cells

Antiproliferative and proapoptotic effects of somatostatin on activated hepatic stellate cells

Hesperetin alleviates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition in vivo and in vitro

Peptide-modified chitosan hydrogels promote skin wound healing by enhancing wound angiogenesis and inhibiting inflammation

Activation of ALDH2 with Low Concentration of Ethanol Attenuates Myocardial Ischemia/Reperfusion Injury in Diabetes Rat Model

TGF-?1 promotes scar fibroblasts proliferation and transdifferentiation via up-regulating MicroRNA-21

Reduced Expression of the Extracellular Calcium-Sensing Receptor (CaSR) Is Associated with Activation of the Renin-Angiotensin System (RAS) to Promote Vascular Remodeling in the Pathogenesis of Essential Hypertension

Preventive Effects of Rhodiola rosea L on Bleomycin-Induced Pulmonary Fibrosis in Rats

Astragalus membranaceus?ameliorates renal interstitial fibrosis by inhibiting tubular epithelial-mesenchymal transition?in vivo?and?in vitro

BMSCs Interactions with Adventitial Fibroblasts Display Smooth Muscle Cell Lineage Potential in Differentiation and Migration That Contributes to Neointimal Formation

Suppression of the increasing level of acetylcholine-stimulated intracellular Ca2+ in guinea pig airway smooth muscle cells by mabuterol

The role of Rho/Rho-kinase pathway and the neuroprotective effects of fasudil in chronic cerebral ischemia

Salidroside protects against bleomycin-induced pulmonary fibrosis: activation of Nrf2-antioxidant signaling, and inhibition of NF-?B and TGF-?1/Smad-2/-3 pathways

Silica promotes the transdifferentiation of rat circulating fibrocytes in vitro

Mest Attenuates CCl4-Induced Liver Fibrosis in Rats by Inhibiting the Wnt/?-Catenin Signaling Pathway

Anti-fibrosis effects of Huisheng oral solution in CCl4-induced hepatic fibrosis in rat

Function of the transforming growth factor-?1/c-Jun N-terminal kinase signaling pathway in the action of thalidomide on a rat model of pulmonary fibrosis

Wang T, He X, Liu X, Liu Y, Zhang W, Huang Q, Liu W, Xiong L, Tan R, Wang H, Zeng H. Front Physiol. 2017 Dec 4;8:1010. doi: 10.3389/fphys.2017.01010. eCollection 2017. Weighted Gene Co-expression Network Analysis Identifies FKBP11 as a Key Regulat...

Gong C, Li L, Qin C, Wu W, Liu Q, Li Y, Gan L, Ou S. J Diabetes Res. 2017;2017:8968523. doi: 10.1155/2017/8968523. Epub 2017 Dec 31.

Gao J, Jiang L, Liang Q, Shi J, Hou D, Tang D, Chen S, Kong D, Wang S. Regen Biomater. 2018 Mar;5(2):105-114. doi: 10.1093/rb/rby003. Epub 2018 Mar 6. The grafts modified by heparinization and catalytic nitric oxide generation used for vascular i...

Lin L, Li R, Cai M, Huang J, Huang W, Guo Y, Yang L, Yang G, Lan T, Zhu K. Oxid Med Cell Longev. 2018 Mar 18;2018:7808656. doi: 10.1155/2018/7808656. eCollection 2018. Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB a...

Yang F, Luo L, Zhu ZD, Zhou X, Wang Y, Xue J, Zhang J, Cai X, Chen ZL, Ma Q, Chen YF, Wang YJ, Luo YY, Liu P, Zhao L. Front Pharmacol. 2017 Dec 19;8:929. doi: 10.3389/fphar.2017.00929. eCollection 2017. Chlorogenic Acid Inhibits Liver Fibrosis by ...

Li Y, Su R, Xu S, Huang Q, Xu H. Neuropsychiatr Dis Treat. 2017 Sep 27;13:2477-2487. doi: 10.2147/NDT.S145069. eCollection 2017. Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides

Huang H, Zhang Q, Liu J, Hao H, Jiang C, Han W. Med Sci Monit. 2017 May 31;23:2644-2653. Granulocyte-Colony Stimulating Factor (G-CSF) Accelerates Wound Healing in Hemorrhagic Shock Rats by Enhancing Angiogenesis and Attenuating Apoptosis

Zhou XL, Xu P, Chen HH, Zhao Y, Shen J, Jiang C, Jiang S, Ni SZ, Xu B, Li L. Sci Rep. 2017 Nov 7;7(1):14727. doi: 10.1038/s41598-017-15239-2. Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via...

Li H, Chen L, Wang T, Wang S, Liu J. PLoS One. 2017 Oct 5;12(10):e0186077. doi: 10.1371/journal.pone.0186077. eCollection 2017. The effect of cavernous nerve traction on erectile function in rats

Wang L, Tu L, Zhang J, Xu K, Qian W. Biomed Res Int. 2017;2017:2540540. doi: 10.1155/2017/2540540. Epub 2017 Jan 29. Stellate Cell Activation and Imbalanced Expression of TGF-β1/TGF-β3 in Acute Autoimmune Liver Lesions Induced by ConA in Mice

Wang X, Cao P, Liu J, Du P, Wang Z, Chen W, Liu C, Wu Y. Med Sci Monit. 2017 Jan 4;23:46-56. 5-Aminolaevulinic Acid-Based Photodynamic Therapy Restrains Pathological Hyperplasia of Fibroblasts

Wang M, Yang F, Qiu R, Zhu M, Zhang H, Xu W, Shen B, Zhu W. The role of mmu‐miR‐155‐5p‐NF‐κB signaling in the education of bone marrow‐derived mesenchymal stem cells by gastric cancer cells

Yi M, Liu B, Tang Y, Li F, Qin W, Yuan X. Biomed Res Int. 2018 Feb 12;2018:4135806. doi: 10.1155/2018/4135806. eCollection 2018. Irradiated Human Umbilical Vein Endothelial Cells Undergo Endothelial-Mesenchymal Transition via the Snail/miR-199a-5p...

Sun L, Xiu M, Wang S, Brigstock DR, Li H, Qu L, Gao R. J Cell Mol Med. 2018 Apr;22(4):2346-2356. doi: 10.1111/jcmm.13526. Epub 2018 Feb 9. Lipopolysaccharide enhances TGF‐β1 signalling pathway and rat pancreatic fibrosis

Pan Y, Liu L, Li S, Wang K, Ke R, Shi W, Wang J, Yan X, Zhang Q, Wang Q, Chai L, Xie X, Li M. Sci Rep. 2018 Feb 26;8(1):3624. doi: 10.1038/s41598-018-21812-0. Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and...

Junfa Yang, Qingxue Liu, Shiyang Cao, Tao Xu, Xiaofeng Li, Dandan Zhou, Linxin Pan, Changyao Li, Cheng Huang, Xiaoming Meng, Lei Zhang, and Xiao Wang. Front Pharmacol. 2018 Jan 12;8:980. doi: 10.3389/fphar.2017.00980. eCollection 2017. MicroRNA-14...

An, Z., Qiao, F., Lu, Q., Ma, Y., Liu, Y., Lu, F., & Xu, Z. (2017). Interleukin-6 downregulated vascular smooth muscle cell contractile proteins via ATG4B-mediated autophagy in thoracic aortic dissection. Heart and Vessels, 32(12), 1523–1535. doi:...

Guo, X., Yan, F., Li, J., Zhang, C., & Bu, P. (2017). SIRT3 attenuates AngII-induced cardiac fibrosis by inhibiting myofibroblasts transdifferentiation via STAT3-NFATc2 pathway. American Journal of Translational Research, 9(7), 3258-3269. Retrieve...

Luo, X., Wang, D., Luo, X., Zhu, X., Wang, G., Ning, Z.,…, & Li, X. (2017). Caveolin 1-related autophagy initiated by aldosterone-induced oxidation promotes liver sinusoidal endothelial cells defenestration. Redox Biology, 13, 508-521. Advance onl...

Li, H., Chen, L., Zhang, M., & Zhang, B. (2017). Cells in 3D-reconstitutued eccrine sweat gland cell spheroids differentiate into gross cystic disease fluid protein 15-expressing dark secretory cells and carbonic anhydrase II-expressing clear secr...

Li, J., Yao, W., Zhang, L., Bao, L., Chen, H., Wang, D.,…Hao, C. (2017). Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophages. Respiratory Research, 18(1), 91. doi: 10.1186/s12931-017-0576-z

Xiao, J., Gong, Y., Chen, Y., Yu, D., Wang, X., Zhang, X.,…Zhao, Z. (2017). IL-6 promotes epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through JAK2/STAT3 signaling pathway. American Journal of Physiology Rena...

Song Q, Liu L, Yu J, Zhang J, Xu M, Sun L, Luo H, Feng Z, Meng G. Eur J Pharmacol. 2017 Apr 13. pii: S0014-2999(17)30273-X. doi: 10.1016/j.ejphar.2017.04.014. Dihydromyricetin attenuated Ang II induced cardiac fibroblasts proliferation related to ...

Zhan K, Bai L, Wu Q, Lei D, Wang G. J Biomed Mater Res A. 2017 Apr 26. doi: 10.1002/jbm.a.36094. Fractal characteristics of the microvascular network: A useful index to assess vascularization level of porous silk fibroin biomaterial.

Shang P, Liu W, Liu T, Zhang Y, Mu F, Zhu Z, Liang L, Zhai X, Ding Y, Li Y, Wen A. Sci Rep. 2016 Dec 23;6:39809. doi: 10.1038/srep39809. Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth...

Cao W, Shi P, Ge JJ. BMC Cardiovasc Disord. 2017 Mar 23;17(1):88. doi: 10.1186/s12872-017-0520-7. miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway.

Baisong Zhao, Yongying Pan, Zixin Wang, Haiping Xu and Xingrong Song. Yonsei Med J. 2017 Jan;58(1):131-138. Hyperbaric Oxygen Pretreatment Improves Cognition and Reduces Hippocampal Damage Via p38 Mitogen-Activated Protein Kinase in a Rat Model

Liu X, Yu H, Yang W, Zhou X, Lu H, Shi D. Cancer Genet Cytogenet. 2010 Mar;197(2):152-7. Doi: 10.1016/J.Cancergencyto.2009.11.005. Mutations Of Nfkbia In Biopsy Specimens From Hodgkin Lymphoma.

Liu Z,, Xu S,, Huang X, Wang J, Gao S, Li H, Zhou C, Ye J, Chen S, Jin Zg, Liu P. Br J Pharmacol. 2015 Dec;172(23):5661-75. Doi: 10.1111/Bph.13068. Epub 2015 Feb 27. Cryptotanshinone, An Orally Bioactive Herbal Compound From Danshen, Attenuates At...

Li J, Ye Y, Zhang R, Zhang L, Hu X, Han D, Chen J, He X, Wang G, Yang X, Wang L. Sci Rep. 2015 May 19;5:9720. Doi: 10.1038/Srep09720. Robo1/2 Regulate Follicle Atresia Through Manipulating Granulosa Cell Apoptosis In Mice.

Yuan W, Yang D, Sun X, Liu W, Wang L, Li X, Man X, Fu Q. Int J Clin Exp Pathol. 2014 Aug 15;7(9):5772-81. Ecollection 2014. Effects Of Hydroxysafflor Yellow A On Proliferation And Collagen Synthesis Of Rat Vascular Adventitial Fibroblasts Induced ...

Bian Eb, Huang C, Ma Tt, Tao H, Zhang H, Cheng C, Lv Xw, Li J. Toxicol Appl Pharmacol. 2012 Oct 1;264(1):13-22. Doi: 10.1016/J.Taap.2012.06.022. Epub 2012 Jul 25. Dnmt1-Mediated Pten Hypermethylation Confers Hepatic Stellate Cell Activation And Li...

Yang L, Ni L, Duan Q, Wang X, Chen C, Chen S, Chaugai S, Zeldin Dc, Tang Jr, Wang Dw. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar;116-117:64-75. Doi: 10.1016/J.Prostaglandins.2015.01.004. Epub 2015 Feb 14. Cyp Epoxygenase 2J2 Prevents Cardiac ...

Yang D, Gao Yh, Tan Kb, Zuo Zx, Yang Wx, Hua X, Li Pj, Zhang Y, Wang G. Gene Ther. 2013 Dec;20(12):1140-8. Doi: 10.1038/Gt.2013.41. Epub 2013 Aug 22. Inhibition Of Hepatic Fibrosis With Artificial Microrna Using Ultrasound And Cationic Liposome-Be...

Li Q, Lv Ll, Wu M, Zhang Xl, Liu H, Liu Bc. J Cell Biochem. 2013 Mar;114(3):632-8. Doi: 10.1002/Jcb.24405. Dexamethasone Prevents Monocyte-Induced Tubular Epithelial-Mesenchymal Transition In Hk-2 Cells.

Tang R, Yang C, Tao Jl, You Yk, An N, Li Sm, Wu Hl, Liu Hf. Cell Biol Int. 2011 Sep;35(9):953-9. Doi: 10.1042/Cbi20100668. Epithelial-Mesenchymal Transdifferentiation Of Renal Tubular Epithelial Cells Induced By Urinary Proteins Requires The Activ...

Wang D, Yin J, Dong R, Zhao J, Wang Q, Wang N, Wang S, Du X, Lu J. Dig Liver Dis. 2015 Apr;47(4):315-23. Doi: 10.1016/J.Dld.2014.12.017. Epub 2015 Jan 12. Inhibition Of Janus Kinase-2 Signalling Pathway Ameliorates Portal Hypertensive Syndrome In ...

Zhou X, Zhang J, Xu C, Wang W. J Pharmacol Sci. 2014;126(4):344-50. Doi: 10.1254/Jphs.14173Fp. Epub 2014 Dec 2. Curcumin Ameliorates Renal Fibrosis By Inhibiting Local Fibroblast Proliferation And Extracellular Matrix Deposition.

Liu P, Li F, Qiu M, He L. Diabetes Res Clin Pract. 2014 Aug;105(2):206-16. Doi: 10.1016/J.Diabres.2014.04.020. Epub 2014 Apr 28. Expression And Cellular Distribution Of Tlr4, Myd88, And Nf-??b In Diabetic Renal Tubulointerstitial Fibrosis, In Vitr...

Liu T, Liu Y, Chen Y, Liu S, Maitz Mf, Wang X, Zhang K, Wang J, Wang Y, Chen J, Huang N. Acta Biomater. 2014 May;10(5):1940-54. Doi: 10.1016/J.Actbio.2013.12.013. Epub 2013 Dec 14. Immobilization Of Heparin/Poly-(L)-Lysine Nanoparticles On Dopamin...

Luo Q, Liu X, Zheng Y, Zhao Y, Zhu J, Zou L. Placenta. 2015 May;36(5):567-74. Doi: 10.1016/J.Placenta.2015.02.009. Epub 2015 Feb 21. Ephrin-B2 Mediates Trophoblast-Dependent Maternal Spiral Artery Remodeling In First Trimester.

Shou Z, Shen L, Xiong P. J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):85-8. Doi: 10.1007/S11596-010-0115-3. Epub 2010 Feb 14. Assessing The Validity Of A Novel Model Of Vertebral Artery Type Of Cervical Syndrome Induced By Injecting Scler...

Hu J, Zhou Z, Shi S, Zhu X, Wang X, Zhang W, Hu S, Qian H, Xu W. Oncol Lett. 2013 Jan;5(1):179-184. Epub 2012 Oct 30. Mesenchymal Stem-Like Cells Isolated From Human Esophageal Carcinoma And Adjacent Non-Cancerous Tissues.

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1 Customer Q&As for Anti-Alpha-Smooth Muscle Actin ACTA2 Antibody (Monoclonal, 1A4)


Our lab want to know about using your anti-Alpha-Smooth Muscle Actin antibody (Monoclonal, 1A4) for r-rno-445355; smooth muscle contraction studies. Has this antibody been tested with western blotting on rat stomach tissue? We would like to see some validation images before ordering.

B. Miller

Verified customer

Asked: 2015-02-02


Thanks for your inquiry. This MA1106 anti-Alpha-Smooth Muscle Actin antibody (Monoclonal, 1A4) is tested on rat stomach tissue, mouse stomach tissue lysates, human placenta tissue. It is guaranteed to work for IHC, WB in human, mouse, rat. Our Boster guarantee will cover your intended experiment even if the sample type has not been be directly tested.

Boster Scientific Support

Answered: 2015-02-02


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