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Product Info Summary
| SKU: | A05771 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-CAPS1 CADPS Antibody
SKU/Catalog Number
A05771
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-CAPS1 CADPS Antibody (Catalog # A05771). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
CAPS1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product
Anti-CAPS1 CADPS Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A05771)
Host
Rabbit
Contents
CAPS1 Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Isotype
IgG
Immunogen
CAPS1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of the human CAPS1. The immunogen is located within the last 50 amino acids of CAPS1.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
Numerous isoforms of CAPS1 are known to exist; the lower molecular weight bands seen in the immunoblot image are likely to be these isoforms. This CAPS1 antibody is predicted to be specific to CAPS1 and not recognize CAPS2.
Reactive Species
A05771 is reactive to CADPS in Human, Mouse, Rat
Applications
A05771 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
152.786kDa
Background of CADPS
CAPS1 and its related protein CAPS2 encode novel neural/endocrine-specific cytosolic and peripheral membrane proteins. Both are essential components of the synaptic vesicle priming machinery and are required for the Ca2+-regulated exocytosis of secretory vesicles; CAPS-deficienct neurons contain no or very few fusion competent synaptic vesicles, causing a selective impairment of fast phasic transmitter release. CAPS1 acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4, 5-bisphosphate and is thought to be a specific regulator of large dense-core vesicle fusion.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
CAPS1 antibody can be used for detection of CAPS1 by Western blot at 0.5 - 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in rat samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of CAPS1 in rat brain tissue lysate with CAPS1 antibody at (A) 0.5 and (B) 1 μg/mL.
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Immunohistochemistry of CAPS1 in human brain with CAPS1 antibody at 5 μg/mL.
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Immunofluorescence of CAPS1 in human brain tissue with CAPS1 antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For CADPS (Source: Uniprot.org, NCBI)
Gene Name
CADPS
Full Name
Calcium-dependent secretion activator 1
Weight
152.786kDa
Alternative Names
Ca++-dependent secretion activator; CADPS1; Calcium-dependent activator protein for secretion 1; calcium-dependent secretion activator 1; CAPS-1; CAPS1Ca2+-dependent secretion activator; CAPSCa2+-dependent activator protein for secretion; KIAA1121Ca2+-regulated cytoskeletal protein CADPS CADPS1, CAPS, CAPS1, UNC-31 calcium dependent secretion activator calcium-dependent secretion activator 1|CAPS-1|Ca++-dependent secretion activator|Ca2+ dependent secretion activator|Ca2+-dependent activator protein for secretion|Ca2+-regulated cytoskeletal protein|calcium-dependent activator protein for secretion 1
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CADPS, check out the CADPS Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CADPS: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-CAPS1 CADPS Antibody (A05771)
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Customer Reviews
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