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Product Info Summary
| SKU: | A02941 |
|---|---|
| Size: | 100ul |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IHC-P, WB, IF (paraffin) |
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Product info
Product Name
Anti-Caspase-4 CASP4 Antibody
SKU/Catalog Number
A02941
Size
100ul
Form
Liquid
Description
Boster Bio Anti-Caspase-4 CASP4 Antibody (Catalog# A02941). Tested in WB, IHC-P, IF (paraffin), ELISA applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
Store at -20°C for one year. For short-term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-Caspase-4 CASP4 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A02941)
Host
Rabbit
Contents
PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
7A7
Isotype
Rabbit IgG
Immunogen
A peptide derived from human Caspase-4. Immunogen sequence location: 75 - 124
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
No cross reactivity with other proteins.
Reactive Species
A02941 is reactive to CASP4 in Human, Mouse, Rat
Applications
A02941 is guaranteed for ELISA, IHC-P, WB, IF (paraffin) Boster Guarantee
Observed Molecular Weight
72 kDa
Calculated molecular weight
43.262kDa
Background of CASP4
Integrin alpha 1 (ITGA1) chain associates with the beta 1 (ITGB1) chain to form a heterodimer that functions as a dual laminin/collagen receptor in neural cells and hematopoietic cells. ITGA1 has a 206-amino acid I domain in its N-terminal half, followed by 3 divalent cation-binding sites and a C-terminal transmembrane domain with a short cytoplasmic tail. It also has 28 potential N-glycosylation sites. Human ITGA1 was expressed in a mouse fibroblast cell line as a 180-kD protein. ITGA1 is involved in the early remodeling of osteoarthritic cartilage and plays an essential role in the regulation of mesenchymal stem cell proliferation and cartilage production. It also plays an essential role in the regulation of MSC proliferation and cartilage production.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Reconsitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Western Blot, 1:500 - 1:2000
Immunohistochemistry, 1:100 - 1:300
ELISA, 1:40000
Not yet tested in other applications.
Validation Images & Assay Conditions
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Western blot analysis of lysate from K562 cells, using Caspase-4 antibody.
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Immunohistochemistry analysis of Caspase-4 antibody in paraffin-embedded human lung carcinoma tissue.
Protein Target Info & Infographic
Gene/Protein Information For CASP4 (Source: Uniprot.org, NCBI)
Gene Name
CASP4
Full Name
Caspase-4
Weight
43.262kDa
Superfamily
peptidase C14A family
Alternative Names
apoptotic cysteine protease Mih1/TX; CASP4; CASP-4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; Caspase4; Caspase-4; EC 3.4.22; EC 3.4.22.57; ICE(rel)II; ICE(rel)-II; ICEREL-II; ICH2; ICH-2; Mih1/TX; Protease ICH-2; Protease TX; TX CASP4 ICE(rel)II, ICEREL-II, ICH-2, Mih1, Mih1/TX, TX caspase 4 caspase-4|CASP-4|ICE and Ced-3 homolog 2|ICE(rel)-II|apoptotic cysteine protease Mih1/TX|caspase 4, apoptosis-related cysteine peptidase|caspase 4, apoptosis-related cysteine protease|caspase-4 isoform alpha|protease ICH-2|protease TX
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CASP4, check out the CASP4 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CASP4: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Caspase-4 CASP4 Antibody (A02941)
Hello CJ!
No publications found for A02941
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Customer Reviews
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