SKU MA1013
Size 100μg/vial
Reactivity Human
Clonality Monoclonal
Clone Number CTD-19
Host Mouse
Ig Isotype Mouse IgG2a
Applications IHC, WB

Overview

Product Name Anti-Cathepsin D Monoclonal Antibody
SKU/Catalog Number MA1013
Storage & Handling At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
Size 100μg/vial
Description Mouse IgG monoclonal antibody for Cathepsin D, cathepsin D (CTSD) detection. Tested with WB, IHC-P in Human. No cross reactivity with other proteins.
Cite This Product Anti-Cathepsin D Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # MA1013)
Host Mouse
Immunogen Human liver cathepsin D.
Reactivity Human

Assay Details

Assay Dilutions Overview

Immunohistochemistry(Paraffin-embedded Section), 1-2μg/ml, Human, By Heat
Western blot, 0.5-1μg/ml, Human

Boster's Secondary Antibodies And IHC, WB Kits

The following reagents are used to generate the images below.

Boster recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P).

Images And Assay Conditions

/antibody/ma1013 1 IHC anti cathepsin d antibody.jpg

Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Intestinal Cancer Tissue

/antibody/ma1013 2 IHC anti cathepsin d antibody.jpg

Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Lung Cancer Tissue

/antibody/ma1013 3 IHC anti cathepsin d antibody.jpg

Anti- Cathepsin D antibody, MA1013, IHC(P)
IHC(P): Human Mammary Cancer Tissue

Target Info

Protein Target Info (Source: Uniprot.org)

Uniprot Id P24268
Gene Name Ctsd
Protein Name Cathepsin D
Tissue Specificity CTSD: Expressed in the aorta extrcellular space (atprotein level).
Alternative Names Cathepsin D;3.4.23.5;Cathepsin D 12 kDa light chain;Cathepsin D 9 kDa light chain;Cathepsin D 34 kDa heavy chain;Cathepsin D 30 kDa heavy chain;Ctsd;
Subcellular Localization Lysosome. Melanosome . Secreted, extracellular space .
Molecular Weight 44681 MW

*if product is indicated to react with multiple species, protein info is based on the human gene.

Ontology

Protein Function Acid protease active in intracellular protein breakdown.
Background Cathepsin D is one of the lysosomal proteinases. It is ubiquitously expressed and is involved in proteolytic degradation, cell invasion, and apoptosis. Cathepsin D is mapped to chromosome 11. The amino acid sequence predicted from the cDNA sequence shows that human cathepsin D consists of 412 amino acids with 20 and 44 amino acids in a pre- and a prosegment, respectively.

Order Product (MA1013)

Promotion:

Buy primary get secondary antibody for free.
Option Price
30ug sample size $99
100ug $280
100ug+Free HRP Secondary BA1050 $280
100ug+Free Biotin Secondary BA1001 $280
Ships in 5-7 business days.

Troubleshooting

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We promise all of our products perform as described in datasheets.

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Publications

Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage checkpoint

Customer Q&As

Q: Is your western blot protocol provided from the website applicable for all your antibodies? Keyword: applications, WB
A: The protocol is applicable for all our antibodies in WB, the NC Membrane(0.45μm or 0.22μm) and transfer time(70 mins or 50 mins) depends on the protein molecular weight, details can be found in included protocol.
Q: Can I conjugate markers to this antibody? Can I link custom conjugates to this antibody? Keyword: conjugation
A: The antibody is stored with BSA and cannot be conjugated with markers. Carrier free antibodies are available upon request. Please contact support@bosterbio.com
Q: Can you provide monoclonal antibodies carrier free?
A: We cannot.
Q: What are some alternative names that could be used to describe this product?
A: One other very common name is cd antibody