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Product Info Summary
| SKU: | A01374 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Human, Mouse, Rat |
| Host: | Rabbit |
| Application: | ELISA, IF, IHC-P, WB |
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Product info
Product Name
Anti-DDC Antibody
View all Dopa Decarboxylase/DDC Antibodies
SKU/Catalog Number
A01374
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-DDC Antibody (Catalog # A01374). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.
Storage & Handling
DDC antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Cite This Product
Anti-DDC Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A01374)
Host
Rabbit
Contents
DDC Antibody is supplied in PBS containing 0.02% sodium azide.
Clonality
Polyclonal
Clone Number
Clone: SK7
Isotype
IgG
Immunogen
DDC antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DDC. The immunogen is located within amino acids 390 - 440 of DDC .
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
DDC antibody is human, mouse and rat reactive.
Reactive Species
A01374 is reactive to DDC in Human, Mouse, Rat
Applications
A01374 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee
Observed Molecular Weight
68 kDa
Calculated molecular weight
53.926kDa
Background of Dopa Decarboxylase/DDC
DOPA decarboxylase (DDC) belongs to the group II decarboxylase family of proteins (1). It is an important protein in the catecholamine biosynthesis pathway. DDC catalyzes the second reaction in the biosynthesis of catecholamines, trace amines and serotonin (1,2). It can form a homodimer and is expressed in the central nervous system (2). DDC can be used as markers for dopaminergic, noradrenergic and serotonergic neurons in a variety of applications including depression, schizophrenia, Parkinson's disease, neuroendocrine tumors and drug abuse (3,4). Defects in DDC gene may cause the autosomal recessive disorder AADC deficiency (4).
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
DDC antibody can be used for detection of DDC by Western blot at 1 - 2 μg/ml.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Validation Images & Assay Conditions
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Western blot analysis of DDC in human lung tissue lysate with DDC antibody at (A) 0.5 and (B) 1 μg/ml.
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Immunohistochemistry of DDC in human lung tissue with DDC antibody at 2.5 μg/mL.
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Immunofluorescence of DDC in human lung tissue with DDC antibody at 20 μg/mL.
Protein Target Info & Infographic
Gene/Protein Information For DDC (Source: Uniprot.org, NCBI)
Gene Name
DDC
Full Name
Aromatic-L-amino-acid decarboxylase
Weight
53.926kDa
Superfamily
group II decarboxylase family
Alternative Names
AADC; AADCaromatic-L-amino-acid decarboxylase; DDC; dopa decarboxylase (aromatic L-amino acid decarboxylase); Dopa Decarboxylase; EC 4.1.1; EC 4.1.1.28 DDC AADC dopa decarboxylase aromatic-L-amino-acid decarboxylase|dopa decarboxylase (aromatic L-amino acid decarboxylase)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on DDC, check out the DDC Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for DDC: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-DDC Antibody (A01374)
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No publications found for A01374
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Customer Reviews
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Customer Q&As
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