Anti-Hu CD24 Purified Monoclonal Antibody

Cd24 antibody

Boster Bio Anti-Hu CD24 Purified Monoclonal Antibody (Catalog# M00373). Tested in Flow Cytometry, IHC-F, MC (CyTOF) application(s). This antibody reacts with Human.

Product Info Summary

SKU: M00373
Size: 0.1 mg
Reactive Species: Human
Host: Mouse
Application: Flow Cytometry, IHC-F, CyTOF

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Product Name

Anti-Hu CD24 Purified Monoclonal Antibody

View all Cd24 Antibodies

SKU/Catalog Number

M00373

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-Hu CD24 Purified Monoclonal Antibody (Catalog# M00373). Tested in Flow Cytometry, IHC-F, MC (CyTOF) application(s). This antibody reacts with Human.

Storage & Handling

Store at 2-8°C. Do not freeze.

Cite This Product

Anti-Hu CD24 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00373)

Host

Mouse

Contents

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Clonality

Monoclonal

Clone Number

SN3

Isotype

Mouse IgG1

Immunogen

Glycoproteins purified from human NALM-1 cell line. The antibody SN3 reacts with CD24, a 35-45 kDa heavily glycosylated cell surface antigen. CD24 is expressed by granulocytes, B lymphocytes and by some activated T cells and T cell malignancies. It is not expressed on human thymocytes.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

M00373 is reactive to Cd24 in Human

Applications

M00373 is guaranteed for Flow Cytometry, IHC-F, CyTOF Boster Guarantee

Observed Molecular Weight

42 kDa

Calculated molecular weight

7.862kDa

Background of Cd24

CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4; it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

Immunohistochemistry (frozen sections): Positive tissue: tonsil.
Flow cytometry: 1-12 µg/ml

Validation Images & Assay Conditions

Gene/Protein Information For Cd24 (Source: Uniprot.org, NCBI)

Gene Name

Cd24

Full Name

Signal transducer CD24

Weight

7.862kDa

Superfamily

CD24 family

Alternative Names

CD 24; CD24 antigen (small cell lung carcinoma cluster 4 antigen); CD24 antigen; CD24 molecule; CD24; CD24A; CD24Asignal transducer CD24; FLJ22950; FLJ43543; MGC75043; Small cell lung carcinoma cluster 4 antigen Cd24|Cd24a|CD24 molecule|signal transducer CD24|CD24 antigen|HSA|heat-stable antigen|nectadrin heat stable antigen

*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".

For more info on Cd24, check out the Cd24 Infographic

Cd24 infographic

We have 30,000+ of these available, one for each gene! Check them out.

In this infographic, you will see the following information for Cd24: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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Order DetailsPrice
M00373

0.1 mg

$319

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*Sample sizes are prepared on demand and will take extra lead time. (cannot be conjugated)
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