Product Info Summary
SKU: | M03281-1 |
---|---|
Size: | 0.1 mg |
Reactive Species: | Human, Primate |
Host: | Mouse |
Application: | Flow Cytometry, IP, IHC-P, WB |
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Product info
Product Name
Anti-Hu CD48 Purified Monoclonal Antibody
View all CD48/SLAMF2 Antibodies
SKU/Catalog Number
M03281-1
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Hu CD48 Purified Monoclonal Antibody (Catalog# M03281-1). Tested in Flow Cytometry, IP, WB, IHC-P application(s). This antibody reacts with Primate, Human.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Hu CD48 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M03281-1)
Host
Mouse
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
MEM-102
Isotype
Mouse IgG1
Immunogen
Raji human Burkitt's lymphoma cell line. The antibody MEM-102 reacts with CD48 (Blast-1), a 40-47 kDa GPI-anchored extracellular membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Cross-reactivity
This antibody does not cross-react with Thy-1.1 alloantigen.
Reactive Species
M03281-1 is reactive to CD48 in Human, Primate
Applications
M03281-1 is guaranteed for Flow Cytometry, IP, IHC-P, WB Boster Guarantee
Observed Molecular Weight
42 kDa
Calculated molecular weight
27.683kDa
Background of CD48/SLAMF2
CD48 (Blast-1) belongs to the CD2 subset of the Ig superfamily, which includes CD2, CD2F-10, CD58, CD84, CD150, CD229, CD244 and others. These molecules bind to the same or another members of their family, thus mediate homotypic or heterotypic adhesion. CD48 is a GPI-anchored protein broadly expressed on hematopoietic cells and serves as a high affinity ligand for 2B4 and low affinity ligand for CD2. 2B4-CD48 interaction among NK cells and NK-T cells regulates cell proliferation. Signaling through CD48 results in eosinophil activation and CD48 expression is increased in several infectious diseases.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 2 μg/ml.
Immunohistochemistry: 5-10 μg/ml.
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For CD48 (Source: Uniprot.org, NCBI)
Gene Name
CD48
Full Name
CD48 antigen
Weight
27.683kDa
Alternative Names
BCM1 surface antigen; BCM1; BCM1Leukocyte antigen MEM-102; BLAST; BLAST1; BLAST1TCT.1; B-lymphocyte activation marker BLAST-1; CD48 antigen (B-cell membrane protein); CD48 antigen; CD48 molecule; CD48; hCD48; mCD48; MEM-102; SLAMF2 CD48 BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48 CD48 molecule CD48 antigen|B-lymphocyte activation marker BLAST-1|BCM1 surface antigen|CD48 antigen (B-cell membrane protein)|SLAM family member 2|TCT.1|leukocyte antigen MEM-102|signaling lymphocytic activation molecule 2
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD48, check out the CD48 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD48: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Hu CD48 Purified Monoclonal Antibody (M03281-1)
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No publications found for M03281-1
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Customer Reviews
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