Anti-IL-1F8 IL36B Antibody

Product Name

Anti-IL-1F8 IL36B Antibody

View all IL-36 beta/IL-1F8 Antibodies

SKU/Catalog Number

A08643

Size

100μl

Form

Liquid

Description

Boster Bio Anti-IL-1F8 IL36B Antibody catalog # A08643. Tested in IHC, WB applications. This antibody reacts with Human.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-IL-1F8 IL36B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08643)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

2G2

Isotype

IgG

Immunogen

The antiserum was produced against synthesized peptide derived from the C-terminal region of human IL36B at amino acid range 111-160

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

No cross reactivity with other proteins.

Reactive Species

A08643 is reactive to IL36B in Human

Applications

A08643 is guaranteed for IHC, WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

18.522kDa

Background of IL-36 beta/IL-1F8

APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G₁ phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000
IHC-P, 1:100-1:300

Validation Images & Assay Conditions

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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung, antibody was diluted at 1:100.

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Western blot analysis of HepG2 cells using IL-1F8 Polyclonal Antibody. Secondary antibody was diluted at 1:20000

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Immunohistochemistry (IHC) analysis of paraffin-embedded Human Lung, antibody was diluted at 1:100.

Gene/Protein Information For IL36B (Source: Uniprot.org, NCBI)

Alternative Names

family of interleukin 1-eta; FIL1 eta; FIL1; FIL1-(ETA); FIL1H; FILI-(ETA); IL-1 eta; IL1-ETA; IL1F8 (Canonical product IL-1F8a); IL-1F8 (FIL1-eta); IL1F8; IL-1F8; IL1H2; IL-1H2; IL36 beta; IL-36 beta; IL36B; interleukin 1 family, member 8 (eta); interleukin 1, eta; Interleukin 36, Beta; Interleukin-1 eta; interleukin-1 family member 8; Interleukin-1 homolog 2; Interleukin-1 Superfamily e; Interleukin-36 Beta IL36B FIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2 interleukin 36 beta interleukin-36 beta|FIL1 eta|IL-1 eta|IL-1F8 (FIL1-eta)|IL1F8 (Canonical product IL-1F8a)|Interleukin-1 Superfamily e|family of interleukin 1-eta|interleukin 1 family, member 8 (eta)|interleukin-1 eta|interleukin-1 family member 8|interleukin-1 homolog 2

For more info on IL36B, check out the IL36B Infographic

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In this infographic, you will see the following information for IL36B: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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