Anti-LAMTOR3 Antibody

Product Name

Anti-LAMTOR3 Antibody

View all MP1/MAP2K1IP1 Antibodies

SKU/Catalog Number

A08040

Size

0.1 mg

Form

Liquid

Description

Boster Bio Anti-LAMTOR3 Antibody (Catalog # A08040). Tested in ELISA, WB, IHC-P, IF applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

LAMTOR3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Cite This Product

Anti-LAMTOR3 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A08040)

Host

Rabbit

Contents

LAMTOR3 Antibody is supplied in PBS containing 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

Clone: SK7

Isotype

IgG

Immunogen

LAMTOR3 antibody was raised against an 15 amino acid peptide near the center of human LAMTOR3. The immunogen is located within amino acids 40 - 90 of LAMTOR3.

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Cross-reactivity

LAMTOR3 antibody is human, mouse and rat reactive. At least two isoforms of LAMTOR3 are known to exist; this antibody will detect both isoforms. LAMTOR3 antibody is predicted to not cross-react with other LAMTOR family proteins.

Reactive Species

A08040 is reactive to LAMTOR3 in Human, Mouse, Rat

Applications

A08040 is guaranteed for ELISA, IF, IHC-P, WB Boster Guarantee

Observed Molecular Weight

68 kDa

Calculated molecular weight

13.623kDa

Background of MP1/MAP2K1IP1

The late endosomal/lysosomal adaptor MAPK and MTOR activator 3 (LAMTOR3) protein belongs to the LAMTOR family of proteins, and together with LAMTOR2 and the MAPK1 and ERK kinase 1 (MEK1) localizes to late endosomes where it is required for the efficient activation of ERK signaling (1,2). This complex is involved in the regulation of late endosomal traffic and cellular proliferation (3) and plays a role in cellular host defense against Salmonella infection (4).

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

LAMTOR3 antibody can be used for detection of LAMTOR3 by Western blot at 1 - 2 μg/ml. Antibody can also be used for Immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.
Antibody validated: Western Blot in human samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.

Validation Images & Assay Conditions

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Western blot analysis of LAMTOR3 in human brain tissue lysate with LAMTOR3 antibody at (A) 1 and (B) 2 μg/ml

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Immunohistochemistry of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 5 μg/mL.

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Immunofluorescence of LAMTOR3 in human brain tissue with LAMTOR3 antibody at 20 μg/mL.

Gene/Protein Information For LAMTOR3 (Source: Uniprot.org, NCBI)

Alternative Names

LAMTOR3; Late endosomal/lysosomal adaptor and MAPK and MTOR activator 3; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; MAP2K1IP1; Mapbp; MAPK scaffold protein 1; MAPKSP1; MEK binding partner 1; MEK partner 1; MEK-binding partner 1; mitogen-activated protein kinase kinase 1 interacting protein 1; Mitogen-activated protein kinase kinase 1-interacting protein 1; Mitogen-activated protein kinase scaffold protein 1; MP1; PRO0633; Ragulator3 LAMTOR3 MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 ragulator complex protein LAMTOR3|MAPK scaffold protein 1|MEK binding partner 1|late endosomal/lysosomal adaptor and MAPK and MTOR activator 3|mitogen-activated protein kinase kinase 1 interacting protein 1|mitogen-activated protein kinase scaffold protein 1

For more info on LAMTOR3, check out the LAMTOR3 Infographic

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In this infographic, you will see the following information for LAMTOR3: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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