Product Info Summary
SKU: | A03642-1 |
---|---|
Size: | 100ul |
Reactive Species: | Human, Mouse, Rat |
Host: | Rabbit |
Application: | IP, IF, IHC, WB |
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Product info
Product Name
Anti-MCM5 (F51) Antibody
SKU/Catalog Number
A03642-1
Size
100ul
Form
Liquid
Description
Boster Bio Anti-MCM5 (F51) Antibody catalog # A03642-1. Tested in WB,IHC,IF,IP applications. This antibody reacts with Human,Mouse,Rat.
Storage & Handling
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Cite This Product
Anti-MCM5 (F51) Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03642-1)
Host
Rabbit
Contents
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2
Clonality
Polyclonal
Isotype
IgG
Immunogen
Synthesized peptide derived from human prostate apoptosis response protein-4.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
A03642-1 is reactive to MCM5 in Human, Mouse, Rat
Applications
A03642-1 is guaranteed for IP, IF, IHC, WB Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
82.286kDa
Background of MCM5
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down-regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Hongzhe Li, J. Biol. Chem., Feb 2007; 282: 4943 - 4950.
Wuhan Xiao, Cancer Res., Aug 2003; 63: 4698 - 4704.
Thierry Virolle, J. Biol. Chem., Mar 2003; 278: 11802 - 11810.
Derek J. Richard, Genes & Dev., Feb 2001; 15: 328.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
WB: 1:500-1:1000
IHC/IF: 1:50-1:200
IP: 1:10-1:100
Validation Images & Assay Conditions
There are currently no images for this product. We are working on uploading them please check back shortly or contact us to expedite our upload process for this antibody.
Protein Target Info & Infographic
Gene/Protein Information For MCM5 (Source: Uniprot.org, NCBI)
Gene Name
MCM5
Full Name
DNA replication licensing factor MCM5
Weight
82.286kDa
Superfamily
MCM family
Alternative Names
CDC46 homolog; CDC46DNA replication licensing factor MCM5; EC 3.6.4.12; MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S.cerevisiae); MCM5 minichromosome maintenance deficient 5, cell division cycle 46; MGC5315; minichromosome maintenance complex component 5; minichromosome maintenance deficient (S. cerevisiae) 5 (cell division cycle 46); minichromosome maintenance deficient 5 (cell division cycle 46); P1-CDC46 MCM5 CDC46, MGORS8, P1-CDC46 minichromosome maintenance complex component 5 DNA replication licensing factor MCM5|CDC46 homolog|MCM5 minichromosome maintenance deficient 5, cell division cycle 46|minichromosome maintenance deficient 5 (cell division cycle 46)
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on MCM5, check out the MCM5 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for MCM5: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-MCM5 (F51) Antibody (A03642-1)
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No publications found for A03642-1
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Customer Reviews
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