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Product Info Summary
| SKU: | M00196-2 |
|---|---|
| Size: | 0.1 mg |
| Reactive Species: | Dog, Mouse |
| Host: | Hamster |
| Application: | Flow Cytometry, IP, IHC-F |
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Product info
Product Name
Anti-Ms CD80 Purified Monoclonal Antibody
SKU/Catalog Number
M00196-2
Size
0.1 mg
Form
Liquid
Description
Boster Bio Anti-Ms CD80 Purified Monoclonal Antibody (Catalog# M00196-2). Tested in Flow Cytometry, IP, IHC-F application(s). This antibody reacts with Mouse, Dog.
Storage & Handling
Store at 2-8°C. Do not freeze.
Cite This Product
Anti-Ms CD80 Purified Monoclonal Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # M00196-2)
Host
Hamster
Contents
Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
Clonality
Monoclonal
Clone Number
16-10A1
Isotype
Armenian Hamster IgG2
Immunogen
CD80-transfected CHO cell line. The Armenian hamster monoclonal antibody 16-10A1 reacts with an extracellular epitope of CD80 (B7-1), a 60 kDa single chain type I glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.
*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.
Reactive Species
M00196-2 is reactive to CD80 in Dog, Mouse
Applications
M00196-2 is guaranteed for Flow Cytometry, IP, IHC-F Boster Guarantee
Observed Molecular Weight
Calculated molecular weight
33.048kDa
Background of B7-1/CD80
CD80 (B7-1) and CD86 (B7-2) are ligands of T cell critical costimulatory molecule CD28 and of an inhibitory receptor CTLA-4 (CD152). The both B7 molecules are expressed on professional antigen-presenting cells and are essential for T cell activation, the both molecules can also substitute for each other in this process. The question what are the differences in CD80 and CD86 competency has not been fully elucidated yet; there are still conflicts in results about their respective roles in initiation or sustaining of the T cell immune response.
Antibody Validation
Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.
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Assay dilution & Images
Assay Dilutions Recommendation
The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.
Flow cytometry: 1-4 μg/ml.
Validation Images & Assay Conditions
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Protein Target Info & Infographic
Gene/Protein Information For CD80 (Source: Uniprot.org, NCBI)
Gene Name
CD80
Full Name
T-lymphocyte activation antigen CD80
Weight
33.048kDa
Alternative Names
Activation B7-1 antigen; B7; B71; B7-1; BB1; CD28LG1; CD28LGB7-1 antigen); CD80 antigen; CD80 molecule; CD80; costimulatory factor CD80; costimulatory molecule variant IgV-CD80; CTLA-4 counter-receptor B7.1; T-lymphocyte activation antigen CD80 CD80 B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7 CD80 molecule T-lymphocyte activation antigen CD80|B-lymphocyte activation antigen B7|CD80 antigen (CD28 antigen ligand 1, B7-1 antigen)|CTLA-4 counter-receptor B7.1|activation B7-1 antigen|costimulatory factor CD80|costimulatory molecule variant IgV-CD80
*If product is indicated to react with multiple species, protein info is based on the gene entry specified above in "Species".For more info on CD80, check out the CD80 Infographic
We have 30,000+ of these available, one for each gene! Check them out.
In this infographic, you will see the following information for CD80: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].
Specific Publications For Anti-Ms CD80 Purified Monoclonal Antibody (M00196-2)
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No publications found for M00196-2
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