Anti-NCX1 SLC8A1 Antibody

Product Name

Anti-NCX1 SLC8A1 Antibody

View all Sodium Calcium Exchanger 1/NCX1 Antibodies

SKU/Catalog Number

A03876

Size

100μl

Form

Liquid

Description

Boster Bio Anti-NCX1 SLC8A1 Antibody catalog # A03876. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-NCX1 SLC8A1 Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A03876)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human NCX1. at AA rangle: 270-350

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A03876 is reactive to SLC8A1 in Human, Mouse, Rat

Applications

A03876 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

39 kDa

Calculated molecular weight

108.547kDa

Background of Sodium Calcium Exchanger 1/NCX1

Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.

Chong J.A.et.al. (1995)Cell 80:949-957
Schoenherr C.J.et.al.(1995)Science 267:1360-1363
Scholl T.et.al.(1996)J. Immunol. 156:1448-1457
Lunyak V.V.et.al. (2002)Science 298:1747-1752

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of extracts from 293 cells, using NCX1 Polyclonal antibody.

Gene/Protein Information For SLC8A1 (Source: Uniprot.org, NCBI)

Alternative Names

FLJ37694; FLJ43417; Na(+)/Ca(2+)-exchange protein 1; sodium/calcium exchanger 1; solute carrier family 8 (sodium/calcium exchanger), member 1 SLC8A1 NCX1 solute carrier family 8 member A1 sodium/calcium exchanger 1|Na(+)/Ca(2+)-exchange protein 1|Na+/Ca++ exchanger|Na+/Ca2+ exchanger|solute carrier family 8 (sodium/calcium exchanger), member 1|solute carrier family 8 member 1

For more info on SLC8A1, check out the SLC8A1 Infographic

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In this infographic, you will see the following information for SLC8A1: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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